Biochemistry
Chapter 8,Enzymes
Yongzhang Luo
罗 永 章
The Protein Chemistry Lab
蛋白质化学实验室
Department of Biological Sciences & Biotechnology
Tsinghua University
清华大学 生物科学与生物技术系
Math Biochemistry Medicine
Smartness
Math Biochemistry Medicine
Smartness
Significance
Math Biochemistry Medicine
Significance
Math Biochemistry Medicine
Smartness + Significance
Math Biochemistry Medicine
Announcement
“Chapter 8 Enzymes,Basic Concepts and Kinetics”
in Lubert Stryer’s,Biochemistry” (Fourth Edition)
will be used as my major lecture material,which is
available for you to Xerox from your TAs,Chapter 8
in Lehninger’s, Principles of Biochemistry” can be
used as a reference.
--- Yongzhang Luo ---
October 20,2002
Chapter 8
in this book
serves as
the lecture
material
Chapter 8
in this book
serves as a
reference
only
Enzymes
Basic Concepts
The two most striking characteristics of enzymes
1) Catalytic capacity
2) Specificity
Actions of Enzymes
1) They bring substrates together in an optimal orientation
2) They catalyze reactions by stabilizing transition states
3) They act as molecular switches
Lehninger
Lehninger