医用细胞工程（二）：第26章组织移植的活细胞制备技术

? 26c F?M±￥%? !/ ? Ba LAK%?!/ ? ? |8 ?f%?i"B? ê? ?r?￥ê %
???%￥V?D %?%M ?]
A?cμ B? ￥ IL-2Hq/
??$o???
i?? èê? ?T¨
#?1 %?y0￥ê % (Lymphokine-activated Killer cells e? LAK
b8? k ￡ ü μú￥ê? ??
 <??b7O? s MHC? ?bYV8??!
iü IL-2?? ?9￥] 8s8￥ %?%
?!B?a
?? ?  üA9 F
7O8?ê? ??9 üA9<
?¨V? ?f E
? ???￥í X|¤ B?￥ r
 e ?? ??Z
üé?? p
μmb LAK%￥?!ZE ? |]8s8??ó
PBL
 ?¨ Ficoll %?%saAs ? %?% ?F? IL- 2(1000IU/mL)(i@F PHA-P 10mg/L) ?37￥è?!???! 5j7? ¨ ? b8?%?!/ ?v  ?9 LAK%  ? 9 à r? 10 9 μ  =a TIL%￥?!/ ? ? V L8 ?F??s ??￥? ???? %?%
Tumor-infiltrating lymphocytes,TIL
8? ü IL-2a
 Vv  ?9i? ? μú ê ?
9μ||N? IL-2a￥ TIL?1 ? ? ?÷￥%
Tumor-dirived activated cell, TDAC

8?ê? ??A÷<? LAK%
] H93 P¨ IL-2
Z V?è üA ￥ F? ?rT
7O?T¨^b ? | L8 ?F? ?g Th? ?Ficolls ? TIL%
?! H?F? LAK?! bT Hq?!
 eò??D LAK?!EM ] m 26-1 TIL￥s?ê?m