BE.410 Spring 2003 - Lecture 4 Slides Images removed due to copyright considerations. See Figures 1 and 2 in Liphardt, Jan, et al. "Reversible Unfolding of Single RNA Molecules by Mechanical Force." Science 292 (27 April 2001). FJC Hooke’s law dsDNA fit to WLC model 100 10 1 0.1 0.01 0 0.2 0.4 0.6 0.8 1.0 1.2 For c e (pN) Extension (x/L) After Bustamante et al., Current Opinion in Structural Biology, 2001