FJC dsDNA 100 10 1 0.1 0.01 Hooke’s law fit to WLC model For c e (pN) 0 0.2 0.4 0.6 0.8 1.0 1.2 Extension (x/L) After Bustamante et al., Current Opinion in Structural Biology, 2001 Graph (Figure 2.) removed due to copyright considerations Images removed due to copyright considerations. See Figures 1, 2, and 3 and Table 1 in Isambert, Herve, et al. "Flexibility of Actin Filaments Derived from Thermal Fluctuations." Journal of Biological Chemistry 270 (19) 12 May 1995, 11437-11444. After Fig. 1 and 2 in Sun, Y. et al. "Mechanical Properties of Single Type II Collagen Molecule." Paper No: 0082, 48th Annual Meeting of the Orthopaoedic Research Society. Image removed due to copyright considerations. Figure 1 in Fujii, T. et al. "Mechanical Properties of Single Hyaluronan Molecules." Paper No: 0390, 48th Annual Meeting of the Orthopaoedic Research Society. Modeling Extreme Extension: Ising Model Cizeau & Viovy 1997 Images removed due to copyright considerations. Image removed due to copyright considerations. Figure 1 in Leger, J. F. et al. "RecA binding to a single double-stranded DNA molecule: A possible role of DNA conformational fluctuations." Proc. Natl. Acad. Sci. USA - Biophysics 95 (Oct 1998) pp. 12295-12299. Images removed due to copyright considerations. Bennink, Martin L. et al. "Unfolding individual nucleosomes by stretching single chromatin fibers with optical tweezers." Nature Structural Biology 8 (7) July 2001. Pulling on Titin "Sawtooth profile" Image removed due to copyright considerations. Figure 1 in Marszalek, Piotr E., et al. "Mechanical unfolding intermediates in titin modules." Nature 402, 100-103 (04 Nov 1999). Image courtesy of the University of Illinois Theoretical and Computational Biophysics Group. (NIH Resource for Macromolecular Modeling and Bioinformatics) Images removed due to copyright considerations. Figures 2 and 3 in Oberhauser, Andres F., et al. "The molecular elasticity of the extracellular matrix protein tenascin." Nature 393 (1998 May 14) 181-5. Assembly of actin at the leading edge of migrating cells