ISSN: 1524-4539 Copyright ? 2005 American Heart Association. All rights reserved. Print ISSN: 0009-7322. Online 72514 Circulation is published by the American Heart Association. 7272 Greenville Avenue, Dallas, TX DOI: 10.1161/CIRCULATIONAHA.105.166553 2005;112;19-34; originally published online Nov 28, 2005; Circulation Part 4: Adult Basic Life Support http://circ.ahajournals.org/cgi/content/full/112/24_suppl/IV-19 located on the World Wide Web at: The online version of this article, along with updated information and services, is http://www.lww.com/static/html/reprints.html Reprints: Information about reprints can be found online at journalpermissions@lww.com Street, Baltimore, MD 21202-2436. Phone 410-5280-4050. Fax: 410-528-8550. Email: Permissions: Permissions & Rights Desk, Lippincott Williams & Wilkins, 351 West Camden http://circ.ahajournals.org/subsriptions/ Subscriptions: Information about subscribing to Circulation is online at by on February 21, 2006 circ.ahajournals.orgDownloaded from Part 4: Adult Basic Life Support B asic life support (BLS) includes recognition of signs of sudden cardiac arrest (SCA), heart attack, stroke, and foreign-body airway obstruction (FBAO); cardiopulmonary resuscitation (CPR); and defibrillation with an automated external defibrillator (AED). This section summarizes BLS guidelines for lay rescuers and healthcare providers. Introduction As noted in Part 3: “Overview of CPR,” SCA is a leading cause of death in the United States and Canada. 1–3 At the first analysis of heart rhythm, about 40% of victims of out-of- hospital SCA demonstrate ventricular fibrillation (VF). 3–5 VF is characterized by chaotic rapid depolarizations and repolar- izations that cause the heart to quiver so that it is unable to pump blood effectively. 6 It is likely that an even larger number of SCA victims have VF or rapid ventricular tachycardia (VT) at the time of collapse, but by the time of first rhythm analysis the rhythm has deteriorated to asystole. 7 Many SCA victims can survive if bystanders act immedi- ately while VF is still present, but successful resuscitation is unlikely once the rhythm deteriorates to asystole. 8 Treatment for VF SCA is immediate bystander CPR plus delivery of a shock with a defibrillator. The mechanism of cardiac arrest in victims of trauma, drug overdose, drowning, and in many children is asphyxia. CPR with both compressions and rescue breaths is critical for resuscitation of these victims. The American Heart Association uses 4 links in a chain (the “Chain of Survival”) to illustrate the important time- sensitive actions for victims of VF SCA (Figure 1). Three and possibly all 4 of these links are also relevant for victims of asphyxial arrest. 9 These links are ● Early recognition of the emergency and activation of the emergency medical services (EMS) or local emergency response system: “phone 911.” 10,11 ● Early bystander CPR: immediate CPR can double or triple the victim’s chance of survival from VF SCA. 8,12–14 ● Early delivery of a shock with a defibrillator: CPR plus defibrillation within 3 to 5 minutes of collapse can produce survival rates as high as 49% to 75%. 15–23 ● Early advanced life support followed by postresuscitation care delivered by healthcare providers. Bystanders can perform 3 of the 4 links in the Chain of Survival. When bystanders recognize the emergency and activate the EMS system, they ensure that basic and advanced life support providers are dispatched to the site of the emergency. In many communities the time interval from EMS call to EMS arrival is 7 to 8 minutes or longer. 24 This means that in the first minutes after collapse the victim’s chance of survival is in the hands of bystanders. Shortening the EMS response interval increases survival from SCA, but the effect is minimal once the EMS response interval (from the time of EMS call until arrival) exceeds 5 to 6 minutes (LOE 3). 25–31 EMS systems should evaluate their protocols for cardiac arrest patients and try to shorten response intervals when improvements are feasible and re- sources are available (Class I). Each EMS system should measure the rate of survival to hospital discharge for victims of VF SCA and use these measurements to document the impact of changes in procedures (Class IIa). 32–35 Victims of cardiac arrest need immediate CPR. CPR provides a small but critical amount of blood flow to the heart and brain. CPR prolongs the time VF is present and increases the likelihood that a shock will terminate VF (defibrillate the heart) and allow the heart to resume an effective rhythm and effective systemic perfusion. CPR is especially important if a shock is not delivered for 4 (LOE 4), 36 5 (LOE 2), 37 or more minutes after collapse. Defibrillation does not “restart” the heart; defibrillation “stuns” the heart, briefly stopping VF and other cardiac electrical activity. If the heart is still viable, its normal pacemakers may then resume firing and produce an effective ECG rhythm that may ultimately produce adequate blood flow. In the first few minutes after successful defibrillation, asystole or bradycardia may be present and the heart may pump ineffectively. In one recent study of VF SCA, only 25% to 40% of victims demonstrated an organized rhythm 60 seconds after shock delivery; it is likely that even fewer had effective perfusion at that point. 38 Therefore, CPR may be needed for several minutes following defibrillation until adequate perfusion is present. 39 Lay rescuers can be trained to use a computerized device called an AED to analyze the victim’s rhythm and deliver a shock if the victim has VF or rapid VT. The AED uses audio and visual prompts to guide the rescuer. It analyzes the victim’s rhythm and informs the rescuer if a shock is needed. AEDs are extremely accurate and will deliver a shock only when VF (or its precursor, rapid VT) is present. 40 AED function and operation are discussed in Part 5: “Electrical Therapies: Automated External Defibrillators, Defibrillation, Cardioversion, and Pacing.” Successful rescuer actions at the scene of an SCA are time critical. Several studies have shown the beneficial effects of immediate CPR and the detrimental impact of delays in defibrillation on survival from SCA. For every minute with- out CPR, survival from witnessed VF SCA decreases 7% to 10%. 8 When bystander CPR is provided, the decrease in survival is more gradual and averages 3% to 4% per minute from collapse to defibrillation. 8,12 CPR has been shown to double 8,12 or triple 41 survival from witnessed SCA at many intervals to defibrillation. 42 (Circulation. 2005;112:IV-19-IV-34.) ? 2005 American Heart Association. This special supplement to Circulation is freely available at http://www.circulationaha.org DOI: 10.1161/CIRCULATIONAHA.105.166553 IV-19 Public access defibrillation and first-responder AED pro- grams may increase the number of SCA victims who receive bystander CPR and early defibrillation, improving survival from out-of-hospital SCA. 43 These programs require an organized and practiced response with rescuers trained and equipped to recognize emergencies, activate the EMS system, provide CPR, and use the AED. 43 Lay rescuer AED programs in airports, 19 on airplanes, 20,21 in casinos, 22 and in first- responder programs with police officers 23,44–46 have achieved survival rates as high as 49% to 75% 19–23 from out-of- hospital witnessed VF SCA with provision of immediate bystander CPR and defibrillation within 3 to 5 minutes of collapse. These high survival rates, however, may not be attained in programs that fail to reduce time to defibrillation. 47–49 Cardiopulmonary Emergencies Emergency Medical Dispatch Emergency medical dispatch is an integral component of the EMS response. 50–53 Dispatchers should receive appropriate training in providing prearrival telephone CPR instructions to callers (Class IIa). 10,54–57 Observational studies (LOE 4) 51,58 and a randomized trial (LOE 2) 57 documented that dispatcher CPR instructions increased the likelihood of bystander CPR being performed. It is not clear if prearrival instructions increase the rate of survival from SCA. 58,59 Dispatchers who provide telephone CPR instructions to bystanders treating children and adult victims with a high likelihood of an asphyxial cause of arrest (eg, drowning) should give directions for rescue breathing followed by chest compressions. In other cases (eg, likely SCA) telephone instruction in chest compressions alone may be preferable (Class IIb). The EMS system’s quality improvement program should include periodic review of the dispatcher CPR instruc- tions provided to specific callers (Class IIa). When dispatchers ask bystanders to determine if breathing is present, bystanders often misinterpret occasional gasps as indicating that the victim is breathing. This erroneous infor- mation can result in failure to initiate CPR for a victim of cardiac arrest (LOE 5). 60 Dispatcher CPR instruction pro- grams should develop strategies to help bystanders identify patients with occasional gasps as likely victims of cardiac arrest and thus increase the likelihood of provision of by- stander CPR for such victims (Class IIb). Acute Coronary Syndromes Coronary heart disease continues to be the nation’s single leading cause of death, with H11022500 000 deaths and 1.2 million patients with an acute myocardial infarction (AMI) annual- ly. 61 Approximately 52% of deaths from AMI occur out of the hospital, most within the first 4 hours after onset of symptoms. 62,63 Early recognition, diagnosis, and treatment of AMI can improve outcome by limiting damage to the heart, 64,65 but treatment is most effective if provided within a few hours of the onset of symptoms. 66,67 Patients at risk for acute coronary syndromes (ACS) and their families should be taught to recognize the signs of ACS and immediately activate the EMS system rather than contact the family physician or drive to the hospital. The classic symptom associated with ACS is chest discomfort, but symptoms may also include discomfort in other areas of the upper body, shortness of breath, sweating, nausea, and lightheadedness. The symptoms of AMI characteristically last more than 15 minutes. Atypical symptoms of ACS are more common in the elderly, women, and diabetic patients. 68–71 To improve ACS outcome, all dispatchers and EMS providers must be trained to recognize ACS symptoms. EMS providers should be trained to determine onset of ACS symptoms, stabilize the patient, and provide prearrival noti- fication and transport to an appropriate medical care facility. EMS providers can support the airway, administer oxygen (Class IIb), and administer aspirin and nitroglycerin. If the patient has not taken aspirin and has no history of aspirin allergy, EMS providers should give the patient 160 to 325 mg of aspirin to chew (Class I) and notify the receiving hospital before arrival. 72–75 Paramedics should be trained and equipped to obtain a 12-lead electrocardiogram (ECG) and transmit the ECG or their interpretation of it to the receiving hospital (Class IIa). More specifics on these topics are covered in Part 8: “Stabilization of the Patient With Acute Coronary Syndromes.” Stroke Stroke is the nation’s No. 3 killer and a leading cause of severe, long-term disability. 61 Fibrinolytic therapy adminis- tered within the first hours of the onset of symptoms limits neurologic injury and improves outcome in selected patients with acute ischemic stroke. 76–78 The window of opportunity is extremely limited, however. Effective therapy requires early Figure 1. Adult Chain of Survival. IV-20 Circulation December 13, 2005 detection of the signs of stroke, prompt activation of the EMS system, prompt dispatch of EMS personnel, rapid delivery to a hospital capable of providing acute stroke care, prearrival notification, immediate and organized hospital care, appro- priate evaluation and testing, and rapid delivery of fibrino- lytic agents to eligible patients. 79,80 Patients at high risk for a stroke and their family members must learn to recognize the signs and symptoms of stroke and to call EMS as soon as they detect any of them. The signs and symptoms of stroke are sudden numbness or weakness of the face, arm, or leg, especially on one side of the body; sudden confusion, trouble speaking or understanding; sudden trouble seeing in one or both eyes; sudden trouble walking, dizziness, loss of balance or coordination; and sudden severe headache with no known cause. 81,82 EMS dispatchers should be trained to suspect stroke and rapidly dispatch responders 83 who should be able to perform an out-of-hospital stroke assessment (LOE 3 to 5; Class IIa), 84–87 establish the time the patient was last known to be “normal,” support the ABCs, notify the receiving hospital that a patient with possible stroke is being transported there, and consider triaging the patient to a facility with a stroke unit (LOE 5 to 8; Class IIb). 88–91 It may be helpful for a family member to accompany the patient during transport to verify the time of symptom onset. If authorized by medical control, EMS providers should check the patient’s glucose level during transport to rule out hypoglycemia as the cause of altered neurologic function and to give glucose if blood sugar is low. When the stroke victim arrives at the emergency depart- ment (ED), the goal of care is to streamline evaluation so that initial assessment is performed within 10 minutes, a com- puted tomography (CT) scan is performed and interpreted within 25 minutes, and fibrinolytics are administered to selected patients within 60 minutes of arrival at the ED and within 3 hours of the onset of symptoms. Additional infor- mation about the assessment of stroke using stroke scales and the management of stroke is included in Part 9: “Adult Stroke.” Adult BLS Sequence The steps of BLS consist of a series of sequential assessments and actions, which are illustrated in the BLS algorithm (Figure 2). The intent of the algorithm is to present the steps in a logical and concise manner that will be easy to learn, remember, and perform. The box numbers in the following section refer to the corresponding boxes in the Adult BLS Healthcare Provider Algorithm. Safety during CPR training and performance, including the use of barrier devices, is discussed in Part 3. Before approach- ing the victim, the rescuer must ensure that the scene is safe. Lay rescuers should move trauma victims only if absolutely necessary (eg, the victim is in a dangerous location, such as a burning building). Check for Response (Box 1) Once the rescuer has ensured that the scene is safe, the rescuer should check for response. To check for response, tap the victim on the shoulder and ask, “Are you all right?” If the victim responds but is injured or needs medical assistance, leave the victim to phone 911. Then return as quickly as possible and recheck the victim’s condition frequently. Activate the EMS System (Box 2) If a lone rescuer finds an unresponsive adult (ie, no move- ment or response to stimulation), the rescuer should activate the EMS system (phone 911), get an AED (if available), and return to the victim to provide CPR and defibrillation if needed. When 2 or more rescuers are present, one rescuer should begin the steps of CPR while a second rescuer activates the EMS system and gets the AED. If the emergency occurs in a facility with an established medical response system, notify that system instead of the EMS system. Healthcare providers may tailor the sequence of rescue actions to the most likely cause of arrest. 92 If a lone healthcare provider sees an adult or child suddenly collapse, the collapse is likely to be cardiac in origin, and the provider should phone 911, get an AED, and return to the victim to provide CPR and use the AED. If a lone healthcare provider aids a drowning victim or other victim of likely asphyxial (primary respira- tory) arrest of any age, the healthcare provider should give 5 cycles (about 2 minutes) of CPR before leaving the victim to activate the EMS system. When phoning 911 for help, the rescuer should be prepared to answer the dispatcher’s questions about location, what happened, number and condition of victims, and type of aid provided. The caller should hang up only when instructed to do so by the dispatcher and should then return to the victim to provide CPR and defibrillation if needed. Open the Airway and Check Breathing (Box 3) To prepare for CPR, place the victim on a hard surface in a face up (supine) position. If an unresponsive victim is face down (prone), roll the victim to a supine (face up) position. If a hospitalized patient with an advanced airway (eg, endotra- cheal tube, laryngeal mask airway [LMA], or esophageal- tracheal combitube [Combitube]) cannot be placed in the supine position (eg, during spinal surgery), the healthcare provider may attempt CPR with the patient in a prone position (Class IIb). See below. Open the Airway: Lay Rescuer The lay rescuer should open the airway using a head tilt–chin lift maneuver for both injured and noninjured victims (Class IIa). The jaw thrust is no longer recommended for lay rescuers because it is difficult for lay rescuers to learn and perform, is often not an effective way to open the airway, and may cause spinal movement (Class IIb). Open the Airway: Healthcare Provider A healthcare provider should use the head tilt–chin lift maneuver to open the airway of a victim without evidence of head or neck trauma. Although the head tilt–chin lift tech- nique was developed using unconscious, paralyzed adult volunteers and has not been studied in victims with cardiac arrest, clinical 93 and radiographic (LOE 3) evidence 94,95 and a case series (LOE 5) 96 have shown it to be effective. Approximately 2% of victims with blunt trauma have a spinal injury, and this risk is tripled if the victim has a Part 4: Adult Basic Life Support IV-21 craniofacial injury, 97 a Glasgow Coma Scale score ofH110218, 98 or both. 97,99 If a healthcare provider suspects a cervical spine injury, open the airway using a jaw thrust without head extension (Class IIb). 96 Because maintaining a patent airway and providing adequate ventilation is a priority in CPR (Class I), use a head tilt–chin lift maneuver if the jaw thrust does not open the airway. Use manual spinal motion restriction rather than immobi- lization devices for victims with suspected spinal injury (Class IIb). 100,101 Manual spinal motion restriction is safer, and immobilization devices may interfere with a patent airway (LOE 3 to 4). 102–104 Cervical collars may complicate airway management during CPR (LOE 4), 102 and they can cause increased intracranial pressure in a victim with a head injury (LOE 4 to 5; Class IIb). 105–108 Spine immobilization devices, however, are necessary during transport. Check Breathing While maintaining an open airway, look, listen, and feel for breathing. If you are a lay rescuer and do not confidently detect normal breathing or if you are a healthcare provider and do not detect adequate breathing within 10 seconds, give 2 breaths (see below). If you are a lay rescuer and you are unwilling or unable to give rescue breaths, begin chest compressions (Class IIa). Professional as well as lay rescuers may be unable to accurately determine the presence or absence of adequate or normal breathing in unresponsive victims (LOE 7) 109–111 because the airway is not open 112 or the victim has occasional gasps, which can occur in the first minutes after SCA and may be confused with adequate breathing. Occasional gasps are not effective breaths. Treat the victim who has occasional gasps as if he or she is not breathing (Class I) and give rescue Figure 2. Adult BLS Healthcare Provider Algorithm. Boxes bordered with dotted lines indicate actions or steps performed by the healthcare provider but not the lay rescuer. IV-22 Circulation December 13, 2005 breaths. CPR training should emphasize how to recognize occasional gasps and should instruct rescuers to give rescue breaths and proceed with the steps of CPR when the unre- sponsive victim demonstrates occasional gasps (Class IIa). Give Rescue Breaths (Boxes 4 and 5A) Give 2 rescue breaths, each over 1 second, with enough volume to produce visible chest rise. This recommended 1-second duration to make the chest rise applies to all forms of ventilation during CPR, including mouth-to-mouth and bag-mask ventilation and ventilation through an advanced airway, with and without supplementary oxygen (Class IIa). During CPR the purpose of ventilation is to maintain adequate oxygenation, but the optimal tidal volume, respira- tory rate, and inspired oxygen concentration to achieve this are not known. The following general recommendations can be made: 1. During the first minutes of VF SCA, rescue breaths are probably not as important as chest compressions 113 be- cause the oxygen level in the blood remains high for the first several minutes after cardiac arrest. In early cardiac arrest, myocardial and cerebral oxygen delivery is limited more by the diminished blood flow (cardiac output) than a lack of oxygen in the blood. During CPR blood flow is provided by chest compressions. Rescuers must be sure to provide effective chest compressions (see below) and minimize any interruption of chest compressions. 2. Both ventilations and compressions are important for victims of prolonged VF SCA, when oxygen in the blood is utilized. Ventilations and compressions are also impor- tant for victims of asphyxial arrest, such as children and drowning victims who are hypoxemic at the time of cardiac arrest. 3. During CPR blood flow to the lungs is substantially reduced, so an adequate ventilation-perfusion ratio can be maintained with lower tidal volumes and respiratory rates than normal. 114 Rescuers should not provide hyperventi- lation (too many breaths or too large a volume). Excessive ventilation is unnecessary and is harmful because it increases intrathoracic pressure, decreases venous return to the heart, and diminishes cardiac output and survival. 115 4. Avoid delivering breaths that are too large or too forceful. Such breaths are not needed and may cause gastric inflation and its resultant complications. 116 The ECC Guidelines 2000 117 recommended a variety of tidal volumes, respiratory rates, and breath delivery intervals. But it is unrealistic to expect the rescuer to distinguish half-second differences in inspiratory times or to judge tidal volumes delivered by mouth-to-mouth or bag-mask ventila- tion. So these guidelines provide simple recommendations for delivery of rescue breaths during cardiac arrest as follows: ● Deliver each rescue breath over 1 second (Class IIa). ● Give a sufficient tidal volume (by mouth-to-mouth/mask or bag mask with or without supplementary oxygen) to produce visible chest rise (Class IIa). ● Avoid rapid or forceful breaths. ● When an advanced airway (ie, endotracheal tube, Combi- tube, or LMA) is in place during 2-person CPR, ventilate at a rate of 8 to 10 breaths per minute without attempting to synchronize breaths between compressions. There should be no pause in chest compressions for delivery of ventila- tions (Class IIa). Studies in anesthetized adults (with normal perfusion) suggest that a tidal volume of 8 to 10 mL/kg maintains normal oxygenation and elimination of CO 2 . During CPR cardiac output is H1101525% to 33% of normal, 118 so oxygen uptake from the lungs and CO 2 delivery to the lungs are also reduced. 119 As a result, low minute ventilation (lower than normal tidal volume and respiratory rate) can maintain effective oxygenation and ventilation during CPR. 120–123 During adult CPR tidal volumes of approximately 500 to 600 mL (6 to 7 mL/kg) should suffice (Class IIa). Although a rescuer cannot estimate tidal volume, this guide may be useful for setting automatic transport ventilators and as a reference for manikin manufacturers. If you are delivering ventilation with a bag and mask, use an adult ventilating bag (volume of 1 to 2 L); a pediatric bag delivers inadequate tidal volume for an adult. 124,125 When giving rescue breaths, give sufficient volume to cause visible chest rise (LOE 6, 7; Class IIa). In 1 observa- tional study trained BLS providers were able to detect “adequate” chest rise in anesthetized, intubated, and para- lyzed adult patients when a tidal volume of approximately 400 mL was delivered. 114 It is likely, however, that a larger volume is required to produce chest rise in a victim with no advanced airway (eg, endotracheal tube, Combitube, LMA) in place. We therefore recommend a tidal volume of 500 to 600 mL but emphasize that the volume delivered should produce visible chest rise (Class IIa). It is reasonable to use the same tidal volume in patients with asphyxial and arrhyth- mic cardiac arrest (Class IIb). Currently manikins show visible chest rise when tidal volumes reach about 700 to 1000 mL. To provide a realistic practice experience, manikins should be designed to achieve a visible chest rise at a tidal volume of 500 to 600 mL. 114 Automated and mechanical ventilators are discussed briefly at the end of this chapter and in Part 6: “CPR Techniques and Devices.” Gastric inflation often develops when ventilation is pro- vided without an advanced airway. It can cause regurgitation and aspiration, and by elevating the diaphragm, it can restrict lung movement and decrease respiratory compliance. 117 Air delivered with each rescue breath can enter the stomach when pressure in the esophagus exceeds the lower esophageal sphincter opening pressure. Risk of gastric inflation is in- creased by high proximal airway pressure 114 and the reduced opening pressure of the lower esophageal sphincter. 126 High pressure can be created by a short inspiratory time, large tidal volume, high peak inspiratory pressure, incomplete airway opening, and decreased lung compliance. 127 To minimize the potential for gastric inflation and its complications, deliver each breath to patients with or without an advanced airway over 1 second and deliver a tidal volume that is sufficient to produce a visible chest rise (Class IIa). But do not deliver more volume or use more force than is needed to produce visible chest rise. Part 4: Adult Basic Life Support IV-23 Mouth-to-Mouth Rescue Breathing Mouth-to-mouth rescue breathing provides oxygen and ven- tilation to the victim. 128 To provide mouth-to-mouth rescue breaths, open the victim’s airway, pinch the victim’s nose, and create an airtight mouth-to-mouth seal. Give 1 breath over 1 second, take a “regular” (not a deep) breath, and give a second rescue breath over 1 second (Class IIb). Taking a regular rather than a deep breath prevents you from getting dizzy or lightheaded. The most common cause of ventilation difficulty is an improperly opened airway, 112 so if the victim’s chest does not rise with the first rescue breath, perform the head tilt–chin lift and give the second rescue breath. 120,121 Mouth-to–Barrier Device Breathing Despite its safety, 129 some healthcare providers 130–132 and lay rescuers may hesitate to give mouth-to-mouth rescue breath- ing and prefer to use a barrier device. Barrier devices may not reduce the risk of infection transmission, 129 and some may increase resistance to air flow. 133,134 If you use a barrier device, do not delay rescue breathing. Barrier devices are available in 2 types: face shields and face masks. Face shields are clear plastic or silicone sheets that reduce direct contact between the victim and rescuer but do not prevent contamination of the rescuer’s side of the shield. 135–137 A rescuer with a duty to respond should use a face shield only as a substitute for mouth-to-mouth breathing. These responders should switch to face mask or bag-mask ventila- tion as soon as possible. 137 Masks used for mouth-to-mask breathing should contain a 1-way valve that directs the rescuer’s breath into the patient while diverting the patient’s exhaled air away from the rescuer. 137 Some masks include an oxygen inlet for administration of supplementary oxygen. When oxygen is available, healthcare providers should provide it at a minimum flow rate of 10 to 12 L/min. Mouth-to-Nose and Mouth-to-Stoma Ventilation Mouth-to-nose ventilation is recommended if it is impossible to ventilate through the victim’s mouth (eg, the mouth is seriously injured), the mouth cannot be opened, the victim is in water, or a mouth-to-mouth seal is difficult to achieve (Class IIa). A case series suggests that mouth-to-nose venti- lation in adults is feasible, safe, and effective (LOE 5). 138 Give mouth-to-stoma rescue breaths to a victim with a tracheal stoma who requires rescue breathing. A reasonable alternative is to create a tight seal over the stoma with a round pediatric face mask (Class IIb). There is no published evidence on the safety, effectiveness, or feasibility of mouth- to-stoma ventilation. One study of patients with laryngecto- mies showed that a pediatric face mask created a better peristomal seal than a standard ventilation bag (LOE 4). 139 Ventilation With Bag and Mask Rescuers can provide bag-mask ventilation with room air or oxygen. A bag-mask device provides positive-pressure ven- tilation without an advanced airway and therefore may produce gastric inflation and its complications (see above). When using a bag-mask device, deliver each breath over a period of 1 second and provide sufficient tidal volume to cause visible chest rise. The Bag-Mask Device A bag-mask device should have the following 140 : a nonjam inlet valve; either no pressure relief valve or a pressure relief valve that can be bypassed; standard 15-mm/22-mm fittings; an oxygen reservoir to allow delivery of high oxygen con- centrations; a nonrebreathing outlet valve that cannot be obstructed by foreign material and will not jam with an oxygen flow of 30 L/min; and the capability to function satisfactorily under common environmental conditions and extremes of temperature. Masks should be made of transparent material to allow detection of regurgitation. They should be capable of creating a tight seal on the face, covering both mouth and nose. Masks should be fitted with an oxygen (insufflation) inlet, have a standard 15-mm/22-mm connector, 141 and should be avail- able in one adult and several pediatric sizes. Bag-Mask Ventilation Bag-mask ventilation is a challenging skill that requires considerable practice for competency. 142,143 The lone rescuer using a bag-mask device should be able to simultaneously open the airway with a jaw lift, hold the mask tightly against the patient’s face, and squeeze the bag. The rescuer must also watch to be sure the chest rises with each breath. Bag-mask ventilation is most effective when provided by 2 trained and experienced rescuers. One rescuer opens the airway and seals the mask to the face while the other squeezes the bag. Both rescuers watch for visible chest rise. 142–144 The rescuer should use an adult (1 to 2 L) bag to deliver a tidal volume sufficient to achieve visible chest rise (Class IIa). If the airway is open and there are no leaks (ie, there is a good seal between face and mask), this volume can be delivered by squeezing a 1-L adult bag about one half to two thirds of its volume or a 2-L adult bag about one-third its volume. As long as the patient does not have an advanced airway in place, the rescuer(s) should deliver cycles of 30 compressions and 2 breaths. The rescuer delivers the breaths during pauses in compressions and delivers each breath over 1 second (Class IIa). The healthcare provider should use supplementary oxygen (O 2 H1102240%, a minimum flow rate of 10 to 12 L/min) when available. Ideally the bag should be attached to an oxygen reservoir to enable delivery of 100% oxygen. Advanced airway devices such as the LMA 145,146 and the esophageal-tracheal combitube 147–149 are currently within the scope of BLS practice in a number of regions (with specific authorization from medical control). These devices may provide acceptable alternatives to bag-mask devices for healthcare providers who are well trained and have sufficient experience to use them (Class IIb). It is not clear that these devices are any more or less complicated to use than a bag and mask; training is needed for safe and effective use of both the bag-mask device and each of the advanced airways. Ventilation With an Advanced Airway When the victim has an advanced airway in place during CPR, 2 rescuers no longer deliver cycles of CPR (ie, IV-24 Circulation December 13, 2005 compressions interrupted by pauses for ventilation). Instead, the compressing rescuer should give continuous chest com- pressions at a rate of 100 per minute without pauses for ventilation. The rescuer delivering ventilation provides 8 to 10 breaths per minute. The 2 rescuers should change com- pressor and ventilator roles approximately every 2 minutes to prevent compressor fatigue and deterioration in quality and rate of chest compressions. When multiple rescuers are present, they should rotate the compressor role about every 2 minutes. Rescuers should avoid excessive ventilation by giving the recommended breaths per minute and limiting tidal volume to achieve chest rise (Class IIa). 115 A translational research study showed that delivery of H1102212 breaths per minute during CPR leads to increased intrathoracic pressure, impeding venous return to the heart during chest compressions. 115 Reduced venous return leads to diminished cardiac output during chest compres- sions and decreased coronary and cerebral perfusion. 150,151 It is critically important that rescuers maintain a ventilation rate of 8 to 10 breaths per minute during CPR and avoid excessive ventilation. 115,150 Automatic Transport Ventilators and Manually Triggered, Flow-Limited Resuscitators Automatic transport ventilators (ATVs) are useful for venti- lation of adult patients with a pulse who have an advanced airway in place, both in and out of the hospital (Class IIa). For the adult cardiac arrest patient who does not have an advanced airway in place, the ATV may be useful if tidal volumes are delivered by a flow-controlled, time-cycled ventilator without positive end-expiratory pressure (PEEP). Manually triggered, oxygen-powered, flow-limited resus- citators may be considered for mask ventilation of the patient who does not have an advanced airway in place during CPR. For further information about these devices see Part 6. Cricoid Pressure Pressure applied to the victim’s cricoid cartilage pushes the trachea posteriorly, compresses the esophagus against the cervical vertebrae, and can prevent gastric inflation and reduce the risk of regurgitation and aspiration. 152,153 Appli- cation of cricoid pressure usually requires a third rescuer, one who is not responsible for chest compressions or ventilations. Cricoid pressure should be used only if the victim is deeply unconscious (ie, has no cough or gag reflex). Pulse Check (for Healthcare Providers) (Box 5) Lay rescuers fail to recognize the absence of a pulse in 10% of pulseless victims (poor sensitivity for cardiac arrest) and fail to detect a pulse in 40% of victims with a pulse (poor specificity). In the ECC Guidelines 2000 117 the pulse check was deleted from training for lay rescuers and deemphasized in training for healthcare providers. There is no evidence, however, that checking for breathing, coughing, or movement is superior for detection of circulation. 154 For ease of training, the lay rescuer will be taught to assume that cardiac arrest is present if the unresponsive victim is not breathing. Healthcare providers also may take too long to check for a pulse 109,155 and have difficulty determining if a pulse is present or absent. The healthcare provider should take no more than 10 seconds to check for a pulse (Class IIa). If a pulse is not definitely felt within 10 seconds, proceed with chest compressions (see below). Rescue Breathing Without Chest Compressions (for Healthcare Providers Only—Box 5A) If an adult victim with spontaneous circulation (ie, palpable pulses) requires support of ventilation, give rescue breaths at a rate of 10 to 12 breaths per minute, or about 1 breath every 5 to 6 seconds (Class IIb). Each breath should be given over 1 second regardless of whether an advanced airway is in place. Each breath should cause visible chest rise. During delivery of rescue breaths, reassess the pulse approximately every 2 minutes (Class IIa), but spend no more than 10 seconds doing so. Chest Compressions (Box 6) Chest compressions consist of rhythmic applications of pres- sure over the lower half of the sternum. These compressions create blood flow by increasing intrathoracic pressure and directly compressing the heart. Although properly performed chest compressions can produce systolic arterial pressure peaks of 60 to 80 mm Hg, diastolic pressure is low 118 and mean arterial pressure in the carotid artery seldom exceeds 40 mm Hg. 118 Blood flow generated by chest compressions delivers a small but critical amount of oxygen and substrate to the brain and myocardium. In victims of VF SCA, chest compressions increase the likelihood that a shock (ie, attempted defibrilla- tion) will be successful. Chest compressions are especially important if the first shock is delivered H113504 minutes after collapse. 36,37,156 Much of the information about the physiology of chest compressions and the effect of varying compression rates, compression-ventilation ratios, and duty cycles (percent of time the chest is compressed versus time allowed for chest recoil) is derived from animal models. Researchers at the 2005 Consensus Conference, 157 however, reached several conclusions about chest compressions: 1. “Effective” chest compressions are essential for providing blood flow during CPR (Class I). 2. To give “effective” chest compressions, “push hard and push fast.” Compress the adult chest at a rate of about 100 compressions per minute, with a compression depth of 1 1 ?2 to 2 inches (approximately 4 to 5 cm). Allow the chest to recoil completely after each compression, and allow ap- proximately equal compression and relaxation times. 3. Minimize interruptions in chest compressions. 4. Further studies are needed to define the best method for coordinating ventilations and chest compressions and to identify the best compression-ventilation ratio in terms of survival and neurologic outcome. Technique To maximize the effectiveness of compressions, the victim should lie supine on a hard surface (eg, backboard or floor), 158 with the rescuer kneeling beside the victim’s tho- rax. 159 The safety and efficacy of over-the-head CPR (OTH- CPR) for lone rescuers and 2-person straddle CPR are unknown, but these techniques may be advantageous in Part 4: Adult Basic Life Support IV-25 confined spaces (LOE 6). 159,160 “CPR-friendly” deflatable mattresses have been studied, and they do not provide an adequate surface on which to perform chest compressions (LOE 6). 161,162 The rescuer should compress the lower half of the victim’s sternum in the center (middle) of the chest, between the nipples. 163 The rescuer should place the heel of the hand on the sternum in the center (middle) of the chest between the nipples and then place the heel of the second hand on top of the first so that the hands are overlapped and parallel (LOE 6; Class IIa). 163–165 Depress the sternum approximately 1 1 ?2 to 2 inches (ap- proximately 4 to 5 cm) and then allow the chest to return to its normal position. Complete chest recoil allows venous return to the heart, is necessary for effective CPR, and should be emphasized in training (Class IIb). 166,167 Compression and chest recoil/relaxation times should be approximately equal (Class IIb). 168–171 In studies of chest compression in out-of- hospital 172 and in-hospital settings, 173 40% of chest compres- sions were of insufficient depth. Rescuers should practice to ensure good chest compressions and should relieve one another every few minutes to reduce the contribution of fatigue to inadequate chest compression depth and rate (see below). There is insufficient evidence from human studies to identify a single optimal chest compression rate. Animal 174 and human 175,176 studies support a chest compression rate of H1102280 compressions per minute to achieve optimal forward blood flow during CPR. We recommend a compression rate of about 100 compressions per minute (Class IIa). Two human observational studies 172,173 showed that inter- ruptions of chest compressions were common. In these studies of healthcare provider CPR, no chest compressions were provided for 24% to 49% 172,173,177 of total arrest time. Interruption of chest compressions in animal models is associated with reduced coronary artery perfusion pressure, and the more frequent or prolonged the interruption, the lower the mean coronary perfusion pressure. In 3 animal studies frequent or prolonged interruptions in chest compressions were associated with reduced return of spontaneous circula- tion (ROSC), reduced survival rates, and reduced postresus- citation myocardial function (LOE 6). 113,174,178,179 Some ani- mal studies suggest that continuous chest compressions with minimal or no interruptions produce higher survival rates than standard CPR (LOE 6). 151,179–181 These guidelines rec- ommend that all rescuers minimize interruption of chest compressions for checking the pulse, analyzing rhythm, or performing other activities (Class IIa). Lay rescuers should continue CPR until an AED arrives, the victim begins to move, or EMS personnel take over CPR (Class IIa). Lay rescuers should no longer interrupt chest compressions to check for signs of circulation or response. Healthcare providers should interrupt chest compressions as infrequently as possible and try to limit interruptions to no longer than 10 seconds except for specific interventions such as insertion of an advanced airway or use of a defibrillator (Class IIa). We strongly recommend that patients not be moved while CPR is in progress unless the patient is in a dangerous environment or is a trauma patient in need of surgical intervention. CPR is better and has fewer interruptions when the resuscitation is conducted where the patient is found. Allow the chest wall to recoil completely after each compression. In studies of CPR in humans 166 and pigs, 167 incomplete chest wall recoil was common, particularly when rescuers were fatigued. 182 Incomplete recoil during BLS CPR is associated with higher intrathoracic pressures, decreased coronary perfusion, and decreased cerebral perfusion (LOE 6). 167 CPR instruction should emphasize the importance of allowing complete chest recoil between compressions. 166 Manikin 168 and animal studies 170,183 suggest that with duty cycles (the compression part of the cycle) of 20% to 50%, coronary and cerebral perfusion increase as the chest com- pression rate increases up to 130 to 150 compressions per minute (LOE 6). 170,183 A duty cycle of 50% is recommended because it is easy to achieve with practice. 168 Rescuer fatigue may lead to inadequate compression rates or depth. Significant fatigue and shallow compressions are seen after 1 minute of CPR, although rescuers may deny that fatigue is present forH113505 minutes (LOE 6). 182 When 2 or more rescuers are available, it is reasonable to switch the compres- sor about every 2 minutes (or after 5 cycles of compressions and ventilations at a ratio of 30:2). Every effort should be made to accomplish this switch in H110215 seconds (Class IIb). If the 2 rescuers are positioned on either side of the patient, one rescuer will be ready and waiting to relieve the “working compressor” every 2 minutes. In the past sternal compression force was gauged as adequate if it generated a palpable carotid or femoral pulse. But a venous pulse may be felt during CPR in the absence of effective arterial blood flow. 110,184 The available evidence suggests that blood flow is optimized by using the recom- mended chest compression force and duration and maintain- ing a chest compression rate of approximately 100 compres- sions per minute. 170 Compression-Ventilation Ratio A compression-ventilation ratio of 30:2 is recommended and further validation of this guideline is needed (Class IIa). 150,151,180,185–187 In infants and children (see Part 11: “Pediatric Basic Life Support”), 2 rescuers should use a ratio of 15:2 (Class IIb). This 30:2 ratio is based on a consensus of experts rather than clear evidence. It is designed to increase the number of compressions, reduce the likelihood of hyperventilation, min- imize interruptions in chest compressions for ventilation, and simplify instruction for teaching and skills retention. A manikin study suggests that rescuers may find a compression- ventilation ratio of 30:2 more tiring than a ratio of 15:2. 182 Further studies are needed to define the best method for coordinating chest compressions and ventilations during CPR and to define the best compression-ventilation ratio in terms of survival and neurologic outcome in patients with or without an advanced airway in place. Once an advanced airway is in place, 2 rescuers no longer deliver cycles of CPR (ie, compressions interrupted by pauses for ventilation). Instead, the compressing rescuer should give continuous chest compressions at a rate of 100 per minute IV-26 Circulation December 13, 2005 without pauses for ventilation. The rescuer delivering venti- lation provides 8 to 10 breaths per minute. The 2 rescuers should change compressor and ventilator roles approximately every 2 minutes to prevent compressor fatigue and deterio- ration in quality and rate of chest compressions. When multiple rescuers are present, they should rotate the compres- sor role about every 2 minutes. The compression rate refers to the speed of compressions, not the actual number of compressions delivered per minute. The actual number of chest compressions delivered per minute is determined by the rate of chest compressions and the number and duration of interruptions to open the airway, deliver rescue breaths, and allow AED analysis. 185,188 Rescu- ers must make every effort to minimize these interruptions in chest compressions. In 1 out-of-hospital study rescuers inter- mittently achieved compression rates of 100 to 121 compres- sions per minute, but the mean number of compressions delivered per minute was reduced to 64 compressions per minute by frequent interruptions. 172 CPR Prompts Evidence from 2 adult studies 172,173 show that the chest compression rate during unprompted CPR is frequently inad- equate in both out-of-hospital and in-hospital settings. Hu- man, 176,189 animal, 190,191 and manikin studies 37,192–196 showed consistent improvement in end-tidal CO 2 and/or quality of CPR in both the out-of-hospital and in-hospital settings when CPR prompt devices were used. A CPR prompt device may be useful in both out-of-hospital and in-hospital settings (Class IIb). Compression-Only CPR The outcome of chest compressions without ventilations is significantly better than the outcome of no CPR for adult cardiac arrest. 113,197–201 In surveys healthcare providers 130–132 as well as lay rescuers 132,202 were reluctant to perform mouth-to-mouth ventilation for unknown victims of cardiac arrest. In observational studies of adults with cardiac arrest treated by lay rescuers, survival rates were better with chest com- pressions only than with no CPR but were best with com- pressions and ventilation (LOE 3 203 ;4 204 ). Some animal studies (LOE 6) 113,197–200,205,206 and extrapolation from clini- cal evidence 207 suggest that rescue breathing is not essential during the first 5 minutes of adult CPR for VF SCA. If the airway is open, occasional gasps and passive chest recoil may provide some air exchange. 186,187,199 In addition, a low minute ventilation may be all that is necessary to maintain a normal ventilation-perfusion ratio during CPR. 208,209 Laypersons should be encouraged to do compression-only CPR if they are unable or unwilling to provide rescue breaths (Class IIa), although the best method of CPR is compressions coordinated with ventilations. Alternative Approaches to Chest Compressions Additional information about alternative CPR techniques and devices can be found in Part 6. “Cough” CPR “Cough” CPR currently has no role when the victim is unresponsive, 210–215 so it has no role in lay rescuer CPR. So-called cough CPR has been reported only in awake monitored patients who develop VF or VT. 216 For more information see Part 6. Prone CPR When the patient cannot be placed in the supine position, rescuers may consider providing CPR with the patient in the prone position, particularly in hospitalized patients with an advanced airway in place (LOE 5; Class IIb). One crossover study of 6 patients (LOE 3) 217 and 3 case reports (LOE 5) 218–220 documented higher blood pressure in hospitalized intubated patients during CPR in the prone position when compared with patients who received CPR in the supine position. Six case series that included 22 intubated hospital- ized patients documented survival to discharge in 10 patients who received CPR in the prone position (LOE 5). 219,220 Defibrillation (Boxes 8, 9, 10) All BLS providers should be trained to provide defibrillation because VF is the most common rhythm found in adults with witnessed, nontraumatic SCA. 7 For these victims survival rates are highest when immediate bystander CPR is provided and defibrillation occurs within 3 to 5 minutes. 8,12–14,19–23 Immediate defibrillation is the treatment of choice for VF of short duration, such as witnessed SCA (Class I). The effect of CPR before defibrillation for prolonged VF SCA has largely been positive. When EMS arrived more than 4 36 to 5 37 minutes after dispatch, a brief period of CPR (1 1 ?2 to 3 minutes) before defibrillation improved ROSC and survival rates for adults with out-of-hospital VF/VT in a before-after study (LOE 3) 36 and a randomized trial (LOE 2). 37 But in another randomized trial in adults with out-of- hospital VF/VT, CPR before defibrillation did not improve ROSC or survival rates (LOE 2). 221 Thus, for adult out-of-hospital cardiac arrest that is not witnessed by the EMS provider, rescuers may give a period of CPR (eg, about 5 cycles or about 2 minutes) before checking the rhythm and attempting defibrillation (Class IIb). In settings with lay rescuer AED programs (AED on-site and available) and for in-hospital environments or if the EMS rescuer witnesses the collapse, the rescuer should use the defibrillator as soon as it is available (Class IIa). Defibrilla- tion is discussed in further detail in Part 5: Electrical Therapies. Special Resuscitation Situations Drowning Drowning is a preventable cause of death. The duration and severity of hypoxia sustained as a result of drowning is the single most important determinant of outcome. Rescuers should provide CPR, particularly rescue breathing, as soon as an unresponsive submersion victim is removed from the water (Class IIa). When rescuing a drowning victim of any age, the lone healthcare provider should give 5 cycles (about 2 minutes) of CPR before leaving the victim to activate the EMS system. Mouth-to-mouth ventilation in the water may be helpful when administered by a trained rescuer (LOE 5; Class IIb). Chest compressions are difficult to perform in water, may not Part 4: Adult Basic Life Support IV-27 be effective, and could potentially cause harm to both the rescuer and the victim. 222,223 There is no evidence that water acts as an obstructive foreign body. Maneuvers to relieve FBAO are not recommended for drowning victims because such maneuvers are not necessary and they can cause injury, vomiting, and aspiration and delay CPR. 224 Rescuers should remove drowning victims from the water by the fastest means available and should begin resuscitation as quickly as possible (Class IIa). Only victims with obvious clinical signs of injury or alcohol intoxication or a history of diving, waterslide use, or trauma should be treated as a “potential spinal cord injury,” with stabilization and possible immobilization of the cervical and thoracic spine. 225–231 Hypothermia In an unresponsive victim with hypothermia, a healthcare provider should assess breathing to confirm respiratory arrest and assess the pulse to confirm cardiac arrest or profound bradycardia for 30 to 45 seconds because heart rate and breathing may be very slow, depending on the degree of hypothermia. If the victim is not breathing, initiate rescue breathing immediately. If the victim does not have a pulse, begin chest compres- sions immediately. Do not wait until the victim is rewarmed to start CPR. To prevent further heat loss, remove wet clothes from the victim; insulate or shield the victim from wind, heat, or cold; and if possible, ventilate the victim with warm, humidified oxygen. Avoid rough movement, and transport the victim to a hospital as soon as possible. If VF is detected, emergency personnel should deliver shocks using the same protocols used for the normothermic cardiac arrest victim (see Part 10.4: “Hypothermia”). For the hypothermic patient in cardiac arrest, continue resuscitative efforts until the patient is evaluated by advanced care providers. In the out-of-hospital setting, passive warm- ing can be used until active warming is available (Class Indeterminate). Recovery Position The recovery position is used for unresponsive adult victims who have normal breathing (Class IIb) and effective circula- tion. This position is designed to maintain a patent airway and reduce the risk of airway obstruction and aspiration. The victim is placed on his or her side with the lower arm in front of the body. There are several variations of the recovery position, each with its own advantages. No single position is perfect for all victims. 232,233 The position should be stable, near a true lateral position, with the head dependent and no pressure on the chest to impair breathing. Although healthy volunteers report compression of vessels and nerves in the dependent limb when the lower arm is placed in front, 234,235 the ease of turning the victim into this position may outweigh the risk. Studies in normal volunteers 236 show that extension of the lower arm above the head and rolling the head onto the arm, while bending both legs, may be feasible for victims with known or suspected spinal injury (LOE 7; Class IIb). 236,237 Foreign-Body Airway Obstruction (Choking) Death from FBAO is an uncommon but preventable cause of death. 238 Most reported cases of FBAO in adults are caused by impacted food and occur while the victim is eating. Most reported episodes of choking in infants and children occur during eating or play, when parents or childcare providers are present. The choking event is therefore commonly witnessed, and the rescuer usually intervenes while the victim is still responsive. Recognition of Foreign-Body Airway Obstruction Because recognition of airway obstruction is the key to successful outcome, it is important to distinguish this emer- gency from fainting, heart attack, seizure, or other conditions that may cause sudden respiratory distress, cyanosis, or loss of consciousness. Foreign bodies may cause either mild or severe airway obstruction. The rescuer should intervene if the choking victim has signs of severe airway obstruction. These include signs of poor air exchange and increased breathing difficulty, such as a silent cough, cyanosis, or inability to speak or breathe. The victim may clutch the neck, demonstrating the universal choking sign. Quickly ask, “Are you choking?” If the victim indicates “yes” by nodding his head without speaking, this will verify that the victim has severe airway obstruction. Relief of Foreign-Body Airway Obstruction When FBAO produces signs of severe airway obstruction, rescuers must act quickly to relieve the obstruction. If mild obstruction is present and the victim is coughing forcefully, do not interfere with the patient’s spontaneous coughing and breathing efforts. Attempt to relieve the obstruction only if signs of severe obstruction develop: the cough becomes silent, respiratory difficulty increases and is accompanied by stridor, or the victim becomes unresponsive. Activate the EMS system quickly if the patient is having difficulty breathing. If more than one rescuer is present, one rescuer should phone 911 while the other rescuer attends to the choking victim. The clinical data on choking is largely retrospective and anecdotal. For responsive adults and children H110221 year of age with severe FBAO, case reports show the feasibility and effectiveness of back blows or “slaps,” 239–241 abdominal thrusts, 239,240,242–247 and chest thrusts. 239,248 Case reports (LOE 5) 242,249,250 and 1 large case series of 229 choking episodes (LOE 5) 239 report that approximately 50% of the episodes of airway obstruction were not relieved by a single technique. The likelihood of success was increased when combinations of back blows or slaps, abdominal thrusts, and chest thrusts were used. Although chest thrusts, back slaps, and abdominal thrusts are feasible and effective for relieving severe FBAO in conscious (responsive) adults and children H113501 year of age, for simplicity in training we recommend that the abdominal thrust be applied in rapid sequence until the obstruction is relieved (Class IIb). If abdominal thrusts are not effective, the rescuer may consider chest thrusts (Class IIb). It is important IV-28 Circulation December 13, 2005 to note that abdominal thrusts are not recommended for infants H110211 year of age because thrusts may cause injuries. Chest thrusts should be used for obese patients if the rescuer is unable to encircle the victim’s abdomen (Class Indeterminate). If the choking victim is in the late stages of pregnancy, the rescuer should use chest thrusts instead of abdominal thrusts (Class Indeterminate). Because abdominal thrusts can cause injury, 251–272 victims of FBAO who are treated with abdominal thrusts should be encouraged to undergo an examination by a physician for injury (Class IIb). Epidemiologic data 238 does not distinguish between FBAO fatalities in which the victims were responsive when first encountered and those in which the victims were unrespon- sive when initially encountered. However, the likelihood that a cardiac arrest or unresponsiveness will be caused by an unsuspected FBAO is thought to be low. 238 If the adult victim with FBAO becomes unresponsive, the rescuer should carefully support the patient to the ground, immediately activate EMS, and then begin CPR. A random- ized trial of maneuvers to open the airway in cadavers 273 and 2 prospective studies in anesthetized volunteers 274,275 show that higher sustained airway pressures can be generated using the chest thrust rather than the abdominal thrust (LOE 7). Each time the airway is opened during CPR, the rescuer should look for an object in the victim’s mouth and remove it. Simply looking into the mouth should not increase the time it takes to attempt the ventilations and proceed to the 30 chest compressions. A healthcare provider should use a finger sweep only when the provider can see solid material obstructing the airway of an unresponsive patient (Class Indeterminate). No studies have evaluated the routine use of the finger sweep to clear an airway in the absence of visible airway obstruction. 95,276,277 The recommendation to use the finger sweep in past guide- lines was based on anecdotal reports that suggested that it was helpful for relieving an airway obstruction. 240,250,251 But 4 case reports have documented harm to the victim 276,277 or rescuer (LOE 7). 95,96 Summary: The Quality of BLS Methods should be developed to improve the quality of CPR delivered at the scene of cardiac arrest by healthcare provid- ers and lay rescuers (Class IIa). These may include education, training, assistance or feedback from biomedical devices, mechanical CPR, and electronic monitoring. Components of CPR known to affect hemodynamics include ventilation rate and duration, compression depth, compression rate and num- ber, complete chest recoil, and hands-off time. Systems that deliver professional CPR should implement processes of continuous quality improvement that include monitoring the quality of CPR delivered at the scene of cardiac arrest, other process-of-care measures (eg, initial rhythm, bystander CPR, and response intervals), and patient outcome up to hospital discharge. This evidence should be used to maximize the quality of CPR delivered (Class Indeterminate). References 1. Zheng ZJ, Croft JB, Giles WH, Mensah GA. Sudden cardiac death in the United States, 1989 to 1998. Circulation. 2001;104:2158–2163. 2. Chugh SS, Jui J, Gunson K, Stecker EC, John BT, Thompson B, Ilias N, Vickers C, Dogra V, Daya M, Kron J, Zheng ZJ, Mensah G, McAnulty J. Current burden of sudden cardiac death: multiple source surveillance versus retrospective death certificate-based review in a large US com- munity. J Am Coll Cardiol. 2004;44:1268–1275. 3. Vaillancourt C, Stiell IG. Cardiac arrest care and emergency medical services in Canada. Can J Cardiol. 2004;20:1081–1090. 4. Cobb LA, Fahrenbruch CE, Olsufka M, Copass MK. Changing incidence of out-of-hospital ventricular fibrillation, 1980–2000. JAMA. 2002;288:3008–3013. 5. Rea TD, Eisenberg MS, Sinibaldi G, White RD. Incidence of EMS- treated out-of-hospital cardiac arrest in the United States. Resuscitation. 2004;63:17–24. 6. Cummins RO. CPR and ventricular fibrillation: lasts longer, ends better. Ann Emerg Med. 1995;25:833–836. 7. Bayes de Luna A, Coumel P, Leclercq JF. Ambulatory sudden cardiac death: mechanisms of production of fatal arrhythmia on the basis of data from 157 cases. Am Heart J. 1989;117:151–159. 8. Larsen MP, Eisenberg MS, Cummins RO, Hallstrom AP. Predicting survival from out-of-hospital cardiac arrest: a graphic model. Ann Emerg Med. 1993;22:1652–1658. 9. Cummins RO, Ornato JP, Thies WH, Pepe PE. Improving survival from sudden cardiac arrest: the “chain of survival” concept. A statement for health professionals from the Advanced Cardiac Life Support Subcom- mittee and the Emergency Cardiac Care Committee, American Heart Association. Circulation. 1991;83:1832–1847. 10. Calle PA, Lagaert L, Vanhaute O, Buylaert WA. Do victims of an out-of-hospital cardiac arrest benefit from a training program for emergency medical dispatchers? Resuscitation. 1997;35:213–218. 11. Curka PA, Pepe PE, Ginger VF, Sherrard RC, Ivy MV, Zachariah BS. Emergency medical services priority dispatch. Ann Emerg Med. 1993; 22:1688–1695. 12. Valenzuela TD, Roe DJ, Cretin S, Spaite DW, Larsen MP. Estimating effectiveness of cardiac arrest interventions: a logistic regression survival model. Circulation. 1997;96:3308–3313. 13. Holmberg M, Holmberg S, Herlitz J. Factors modifying the effect of bystander cardiopulmonary resuscitation on survival in out-of-hospital cardiac arrest patients in Sweden. Eur Heart J. 2001;22:511–519. 14. Holmberg M, Holmberg S, Herlitz J, Gardelov B. Survival after cardiac arrest outside hospital in Sweden. Swedish Cardiac Arrest Registry. Resuscitation. 1998;36:29–36. 15. Weaver WD, Hill D, Fahrenbruch CE, Copass MK, Martin JS, Cobb LA, Hallstrom AP. Use of the automatic external defibrillator in the man- agement of out-of-hospital cardiac arrest. NEnglJMed. 1988;319: 661–666. 16. Auble TE, Menegazzi JJ, Paris PM. Effect of out-of-hospital defibril- lation by basic life support providers on cardiac arrest mortality: a metaanalysis. Ann Emerg Med. 1995;25:642–658. 17. Stiell IG, Wells GA, DeMaio VJ, Spaite DW, Field BJ III, Munkley DP, Lyver MB, Luinstra LG, Ward R. Modifiable factors associated with improved cardiac arrest survival in a multicenter basic life support/ defibrillation system: OPALS Study Phase I results. Ontario Prehospital Advanced Life Support. Ann Emerg Med. 1999;33:44–50. 18. Stiell IG, Wells GA, Field BJ, Spaite DW, De Maio VJ, Ward R, Munkley DP, Lyver MB, Luinstra LG, Campeau T, Maloney J, Dagnone E. Improved out-of-hospital cardiac arrest survival through the inex- pensive optimization of an existing defibrillation program: OPALS study phase II. Ontario Prehospital Advanced Life Support. JAMA. 1999;281:1175–1181. 19. Caffrey SL, Willoughby PJ, Pepe PE, Becker LB. Public use of automated external defibrillators. N Engl J Med. 2002;347:1242–1247. 20. O’Rourke MF, Donaldson E, Geddes JS. An airline cardiac arrest program. Circulation. 1997;96:2849–2853. 21. Page RL, Hamdan MH, McKenas DK. Defibrillation aboard a com- mercial aircraft. Circulation. 1998;97:1429–1430. 22. Valenzuela TD, Roe DJ, Nichol G, Clark LL, Spaite DW, Hardman RG. Outcomes of rapid defibrillation by security officers after cardiac arrest in casinos. N Engl J Med. 2000;343:1206–1209. 23. White RD, Bunch TJ, Hankins DG. Evolution of a community-wide early defibrillation programme experience over 13 years using police/fire personnel and paramedics as responders. Resuscitation. 2005;65:279–83. 24. Eisenberg MS, Horwood BT, Cummins RO, Reynolds-Haertle R, Hearne TR. Cardiac arrest and resuscitation: a tale of 29 cities. Ann Emerg Med. 1990;19:179–86. 25. Braun O, McCallion R, Fazackerley J. Characteristics of midsized urban EMS systems. Ann Emerg Med. 1990;19:536–546. 26. MacDonald RD, Mottley JL, Weinstein C. Impact of prompt defibril- lation on cardiac arrest at a major international airport. Prehosp Emerg Care. 2002;6:1–5. Part 4: Adult Basic Life Support IV-29 27. Nichol G, Detsky AS, Stiell IG, O’Rourke K, Wells G, Laupacis A. Effectiveness of emergency medical services for victims of out-of- hospital cardiac arrest: a metaanalysis. Ann Emerg Med. 1996;27: 700–710. 28. Nichol G, Laupacis A, Stiell IG, O’Rourke K, Anis A, Bolley H, Detsky AS. Cost-effectiveness analysis of potential improvements to emergency medical services for victims of out-of-hospital cardiac arrest. Ann Emerg Med. 1996;27:711–720. 29. Nichol G, Stiell IG, Laupacis A, Pham B, De Maio VJ, Wells GA. A cumulative meta-analysis of the effectiveness of defibrillator-capable emergency medical services for victims of out-of-hospital cardiac arrest. Ann Emerg Med. 1999;34:517–525. 30. Nichol G, Valenzuela T, Roe D, Clark L, Huszti E, Wells GA. Cost effectiveness of defibrillation by targeted responders in public settings. Circulation. 2003;108:697–703. 31. Sweeney TA, Runge JW, Gibbs MA, Raymond JM, Schafermeyer RW, Norton HJ, Boyle-Whitesel MJ. EMT defibrillation does not increase survival from sudden cardiac death in a two-tiered urban-suburban EMS system. Ann Emerg Med. 1998;31:234–240. 32. Cummins RO, Chamberlain DA. The Utstein Abbey and survival from cardiac arrest: what is the connection? Ann Emerg Med. 1991;20:918–919. 33. Cummins RO. The Utstein style for uniform reporting of data from out-of-hospital cardiac arrest. Ann Emerg Med. 1993;22:37–40. 34. Zaritsky A, Nadkarni V, Hazinski M, Foltin G, Quan L, Wright J, Fiser D, Zideman D, O’Malley P, Chameides L, Cummins R. Recommended guidelines for uniform reporting of pediatric advanced life support: the pediatric Utstein style. Circulation. 1995;92:2006–2020. 35. Jacobs I, Nadkarni V, Bahr J, Berg RA, Billi JE, Bossaert L, Cassan P, Coovadia A, D’Este K, Finn J, Halperin H, Handley A, Herlitz J, Hickey R, Idris A, Kloeck W, Larkin GL, Mancini ME, Mason P, Mears G, Monsieurs K, Montgomery W, Morley P, Nichol G, Nolan J, Okada K, Perlman J, Shuster M, Steen PA, Sterz F, Tibballs J, Timerman S, Truitt T, Zideman D. Cardiac arrest and cardiopulmonary resuscitation outcome reports: update and simplification of the Utstein templates for resuscitation registries: a statement for healthcare professionals from a task force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian Resuscitation Council, New Zealand Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Councils of Southern Africa). Circulation. 2004;110:3385–3397. 36. Cobb LA, Fahrenbruch CE, Walsh TR, Copass MK, Olsufka M, Breskin M, Hallstrom AP. Influence of cardiopulmonary resuscitation prior to defibrillation in patients with out-of-hospital ventricular fibrillation. JAMA. 1999;281:1182–1188. 37. Wik L, Hansen TB, Fylling F, Steen T, Vaagenes P, Auestad BH, Steen PA. Delaying defibrillation to give basic cardiopulmonary resuscitation to patients with out-of-hospital ventricular fibrillation: a randomized trial. JAMA. 2003;289:1389–1395. 38. Carpenter J, Rea TD, Murray JA, Kudenchuk PJ, Eisenberg MS. Defi- brillation waveform and post-shock rhythm in out-of-hospital ventricu- lar fibrillation cardiac arrest. Resuscitation. 2003;59:189–96. 39. White RD, Russell JK. Refibrillation, resuscitation and survival in out- of-hospital sudden cardiac arrest victims treated with biphasic automated external defibrillators. Resuscitation. 2002;55:17–23. 40. Kerber RE, Becker LB, Bourland JD, Cummins RO, Hallstrom AP, Michos MB, Nichol G, Ornato JP, Thies WH, White RD, Zuckerman BD. Automatic external defibrillators for public access defibrillation: recommendations for specifying and reporting arrhythmia analysis algorithm performance, incorporating new waveforms, and enhancing safety. A statement for health professionals from the American Heart Association Task Force on Automatic External Defibrillation, Subcom- mittee on AED Safety and Efficacy. Circulation. 1997;95:1677–1682. 41. Holmberg M, Holmberg S, Herlitz J. Effect of bystander cardiopulmo- nary resuscitation in out-of-hospital cardiac arrest patients in Sweden. Resuscitation. 2000;47:59–70. 42. Swor RA, Jackson RE, Cynar M, Sadler E, Basse E, Boji B, Rivera- Rivera EJ, Maher A, Grubb W, Jacobson R, et al. Bystander CPR, ventricular fibrillation, and survival in witnessed, unmonitored out-of- hospital cardiac arrest. Ann Emerg Med. 1995;25:780–784. 43. The Public Access Defibrillation Trial Investigators. Public-access defi- brillation and survival after out-of-hospital cardiac arrest. N Engl J Med. 2004;351:637–646. 44. White RD, Asplin BR, Bugliosi TF, Hankins DG. High discharge survival rate after out-of-hospital ventricular fibrillation with rapid defibrillation by police and paramedics. Ann Emerg Med. 1996;28:480–485. 45. White RD, Hankins DG, Bugliosi TF. Seven years’ experience with early defibrillation by police and paramedics in an emergency medical services system. Resuscitation. 1998;39:145–151. 46. Mosesso VN Jr, Davis EA, Auble TE, Paris PM, Yealy DM. Use of automated external defibrillators by police officers for treatment of out-of-hospital cardiac arrest. Ann Emerg Med. 1998;32:200–207. 47. Groh WJ, Newman MM, Beal PE, Fineberg NS, Zipes DP. Limited response to cardiac arrest by police equipped with automated external defibrillators: lack of survival benefit in suburban and rural Indiana–the police as responder automated defibrillation evaluation (PARADE). Acad Emerg Med. 2001;8:324–330. 48. van Alem AP, Waalewijn RA, Koster RW, de Vos R. Assessment of quality of life and cognitive function after out-of-hospital cardiac arrest with successful resuscitation. Am J Cardiol. 2004;93:131–135. 49. Sayre M, Evans J, White L, Brennan T. Providing automated external defibrillators to urban police officers in addition to fire department rapid defibrillation program is not effective. Resuscitation. In press. 50. Pepe PE, Zachariah BS, Sayre MR, Floccare D. Ensuring the chain of recovery for stroke in your community. Chain of Recovery Writing Group. Prehosp Emerg Care. 1998;2:89–95. 51. Bang A, Biber B, Isaksson L, Lindqvist J, Herlitz J. Evaluation of dispatcher-assisted cardiopulmonary resuscitation. Eur J Emerg Med. 1999;6:175–183. 52. Becker LB, Pepe PE. Ensuring the effectiveness of community-wide emergency cardiac care. Ann Emerg Med. 1993;22:354–365. 53. Zachariah BS, Pepe PE. The development of emergency medical dispatch in the USA: a historical perspective. Eur J Emerg Med. 1995; 2:109–112. 54. Emergency medical dispatching: rapid identification and treatment of acute myocardial infarction. National Heart Attack Alert Program Coor- dinating Committee Access to Care Subcommittee. Am J Emerg Med. 1995;13:67–73. 55. Nordberg M. Emergency medical dispatch: a changing profession. Emerg Med Serv. 1998;27:25–26, 28–34. 56. Nordberg M. NAEMD (National Academy of Emergency Medical Dispatch) strives for universal certification. Emerg Med Serv. 1999;28:45–46. 57. Hallstrom A, Cobb L, Johnson E, Copass M. Cardiopulmonary resus- citation by chest compression alone or with mouth-to-mouth ventilation. N Engl J Med. 2000;342:1546–1553. 58. Culley LL, Clark JJ, Eisenberg MS, Larsen MP. Dispatcher-assisted telephone CPR: common delays and time standards for delivery. Ann Emerg Med. 1991;20:362–366. 59. Bang A, Herlitz J, Holmberg S. Possibilities of implementing dispatcher-assisted cardiopulmonary resuscitation in the community: an evaluation of 99 consecutive out-of-hospital cardiac arrests. Resusci- tation. 2000;44:19–26. 60. Hauff SR, Rea TD, Culley LL, Kerry F, Becker L, Eisenberg MS. Factors impeding dispatcher-assisted telephone cardiopulmonary resus- citation. Ann Emerg Med. 2003;42:731–737. 61. American Heart Association. Heart Disease and Stroke Statistics—2005 Update. Dallas, Tex.: American Heart Association. 2005. 62. American Heart Association in collaboration with International Liaison Committee on Resuscitation. Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care: International Con- sensus on Science, Part 7: the Era of Reperfusion: Section 1: Acute Coronary Syndromes (Acute Myocardial Infarction). Circulation. 2000; 102(suppl I):I-172–I-203. 63. Chiriboga D, Yarzebski J, Goldberg RJ, Gore JM, Alpert JS. Temporal trends (1975 through 1990) in the incidence and case-fatality rates of primary ventric- ular fibrillation complicating acute myocardial infarction: a communitywide perspective. Circulation. 1994;89:998–1003. 64. Anderson JL, Karagounis LA, Califf RM. Metaanalysis of five reported studies on the relation of early coronary patency grades with mortality and outcomes after acute myocardial infarction. Am J Cardiol. 1996;78:1–8. 65. Franzosi MG, Santoro E, De Vita C, Geraci E, Lotto A, Maggioni AP, Mauri F, Rovelli F, Santoro L, Tavazzi L, Tognoni G. Ten-year follow-up of the first megatrial testing thrombolytic therapy in patients with acute myocardial infarction: results of the Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto-1 study. The GISSI Investi- gators. Circulation. 1998;98:2659–2665. 66. Brouwer MA, Martin JS, Maynard C, Wirkus M, Litwin PE, Verheugt FW, Weaver WD. Influence of early prehospital thrombolysis on mor- tality and event-free survival (the Myocardial Infarction Triage and Intervention [MITI] Randomized Trial). MITI Project Investigators. Am J Cardiol. 1996;78:497–502. 67. Raitt MH, Maynard C, Wagner GS, Cerqueira MD, Selvester RH, Weaver WD. Relation between symptom duration before thrombolytic therapy and final myocardial infarct size. Circulation. 1996;93:48–53. 68. Douglas PS, Ginsburg GS. The evaluation of chest pain in women. N Engl J Med. 1996;334:1311–1315. 69. Solomon CG, Lee TH, Cook EF, Weisberg MC, Brand DA, Rouan GW, Goldman L. Comparison of clinical presentation of acute myocardial IV-30 Circulation December 13, 2005 infarction in patients older than 65 years of age to younger patients: the Multicenter Chest Pain Study experience. Am J Cardiol. 1989;63:772–776. 70. Peberdy MA, Ornato JP. Coronary artery disease in women. Heart Dis Stroke. 1992;1:315–319. 71. Sullivan AK, Holdright DR, Wright CA, Sparrow JL, Cunningham D, Fox KM. Chest pain in women: clinical, investigative, and prognostic features. BMJ. 1994;308:883–886. 72. Haynes BE, Pritting J. A rural emergency medical technician with selected advanced skills. Prehosp Emerg Care. 1999;3:343–346. 73. Funk D, Groat C, Verdile VP. Education of paramedics regarding aspirin use. Prehosp Emerg Care. 2000;4:62–64. 74. Freimark D, Matetzky S, Leor J, Boyko V, Barbash IM, Behar S, Hod H. Timing of aspirin administration as a determinant of survival of patients with acute myocardial infarction treated with thrombolysis. Am J Cardiol. 2002;89:381–385. 75. Verheugt FW, van der Laarse A, Funke-Kupper AJ, Sterkman LG, Galema TW, Roos JP. Effects of early intervention with low-dose aspirin (100 mg) on infarct size, reinfarction and mortality in anterior wall acute myocardial infarction. Am J Cardiol. 1990;66:267–270. 76. Grotta JC, Chiu D, Lu M, Patel S, Levine SR, Tilley BC, Brott TG, Haley EC Jr, Lyden PD, Kothari R, Frankel M, Lewandowski CA, Libman R, Kwiatkowski T, Broderick JP, Marler JR, Corrigan J, Huff S, Mitsias P, Talati S, Tanne D. Agreement and variability in the interpre- tation of early CT changes in stroke patients qualifying for intravenous rtPA therapy. Stroke. 1999;30:1528–1533. 77. Ingall TJ, O’Fallon WM, Asplund K, Goldfrank LR, Hertzberg VS, Louis TA, Christianson TJ. Findings from the reanalysis of the NINDS tissue plasminogen activator for acute ischemic stroke treatment trial. Stroke. 2004;35:2418–2424. 78. Kwiatkowski TG, Libman RB, Frankel M, Tilley BC, Morgenstern LB, Lu M, Broderick JP, Lewandowski CA, Marler JR, Levine SR, Brott T. Effects of tissue plasminogen activator for acute ischemic stroke at one year. National Institute of Neurological Disorders and Stroke Recom- binant Tissue Plasminogen Activator Stroke Study Group. N Engl J Med. 1999;340:1781–1787. 79. A systems approach to immediate evaluation and management of hyperacute stroke: experience at eight centers and implications for community practice and patient care. The National Institute of Neuro- logical Disorders and Stroke (NINDS) rt-PA Stroke Study Group. Stroke. 1997;28:1530–1540. 80. Broderick JP, Hacke W. Treatment of acute ischemic stroke, part II: neuroprotection and medical management. Circulation. 2002;106: 1736–1740. 81. Barsan WG, Brott TG, Olinger CP, Adams HP Jr, Haley EC Jr, Levy DE. Identification and entry of the patient with acute cerebral infarction. Ann Emerg Med. 1988;17:1192–1195. 82. Barsan WG, Brott TG, Broderick JP, Haley EC, Levy DE, Marler JR. Time of hospital presentation in patients with acute stroke. Arch Intern Med. 1993;153:2558–2561. 83. Zachariah B, Dunford J, Van Cott CC. Dispatch life support and the acute stroke patient: making the right call. In: Proceedings of the National Institute of Neurological Disorders and Stroke. Bethesda, Md: National Institute of Neurological Disorders and Stroke; 1991:29–33. 84. Smith WS, Isaacs M, Corry MD. Accuracy of paramedic identification of stroke and transient ischemic attack in the field. Prehosp Emerg Care. 1998;2:170–175. 85. Kidwell CS, Starkman S, Eckstein M, Weems K, Saver JL. Identifying stroke in the field: prospective validation of the Los Angeles prehospital stroke screen (LAPSS). Stroke. 2000;31:71–76. 86. Kothari R, Barsan W, Brott T, Broderick J, Ashbrock S. Frequency and accuracy of prehospital diagnosis of acute stroke. Stroke. 1995;26:937–941. 87. Smith WS, Corry MD, Fazackerley J, Isaacs SM. Improved paramedic sensitivity in identifying stroke victims in the prehospital setting. In: Prehosp Emerg Care; 1999:207–210. 88. Merino JG, Silver B, Wong E, Foell B, Demaerschalk B, Tamayo A, Poncha F, Hachinski V. Extending tissue plasminogen activator use to community and rural stroke patients. Stroke. 2002;33:141–146. 89. Chapman KM, Woolfenden AR, Graeb D, Johnston DC, Beckman J, Schulzer M, Teal PA. Intravenous tissue plasminogen activator for acute ischemic stroke: a Canadian hospital’s experience. Stroke. 2000;31: 2920–2924. 90. Cross DT III, Tirschwell DL, Clark MA, Tuden D, Derdeyn CP, Moran CJ, Dacey RG Jr. Mortality rates after subarachnoid hemorrhage: vari- ations according to hospital case volume in 18 states. J Neurosurg. 2003;99:810–817. 91. Riopelle RJ, Howse DC, Bolton C, Elson S, Groll DL, Holtom D, Brunet DG, Jackson AC, Melanson M, Weaver DF. Regional access to acute ischemic stroke intervention. Stroke. 2001;32:652–655. 92. Hazinski MF. Is pediatric resuscitation unique? Relative merits of early CPR and ventilation versus early defibrillation for young victims of prehospital cardiac arrest. Ann Emerg Med. 1995;25:540–543. 93. Guildner CW. Resuscitation: opening the airway. A comparative study of techniques for opening an airway obstructed by the tongue. JACEP. 1976;5:588–590. 94. Greene DG, Elam JO, Dobkin AB, Studley CL. Cinefluorographic study of hyperextension of the neck and upper airway patency. JAMA. 1961;176: 570–573. 95. Ruben HM, Elam JO, Ruben AM, Greene DG. Investigation of upper airway problems in resuscitation, 1: studies of pharyngeal x-rays and performance by laymen. Anesthesiology. 1961;22:271–279. 96. Elam JO, Greene DG, Schneider MA, Ruben HM, Gordon AS, Hustead RF, Benson DW, Clements JA, Ruben A. Head-tilt method of oral resuscitation. JAMA. 1960;172:812–815. 97. Hackl W, Hausberger K, Sailer R, Ulmer H, Gassner R. Prevalence of cervical spine injuries in patients with facial trauma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001;92:370–376. 98. Demetriades D, Charalambides K, Chahwan S, Hanpeter D, Alo K, Velmahos G, Murray J, Asensio J. Nonskeletal cervical spine injuries: epidemiology and diagnostic pitfalls. J Trauma. 2000;48:724–727. 99. Holly LT, Kelly DF, Counelis GJ, Blinman T, McArthur DL, Cryer HG. Cervical spine trauma associated with moderate and severe head injury: incidence, risk factors, and injury characteristics. J Neurosurg Spine. 2002;96:285–291. 100. Majernick TG, Bieniek R, Houston JB, Hughes HG. Cervical spine movement during orotracheal intubation. Ann Emerg Med. 1986;15: 417–420. 101. Lennarson PJ, Smith DW, Sawin PD, Todd MM, Sato Y, Traynelis VC. Cervical spinal motion during intubation: efficacy of stabilization maneuvers in the setting of complete segmental instability. J Neurosurg Spine. 2001;94:265–270. 102. Heath KJ. The effect of laryngoscopy of different cervical spine immo- bilisation techniques. Anaesthesia. 1994;49:843–845. 103. Hastings RH, Wood PR. Head extension and laryngeal view during laryngoscopy with cervical spine stabilization maneuvers. Anesthe- siology. 1994;80:825–831. 104. Gerling MC, Davis DP, Hamilton RS, Morris GF, Vilke GM, Garfin SR, Hayden SR. Effects of cervical spine immobilization technique and laryngoscope blade selection on an unstable cervical spine in a cadaver model of intubation. Ann Emerg Med. 2000;36:293–300. 105. Davies G, Deakin C, Wilson A. The effect of a rigid collar on intra- cranial pressure. Injury. 1996;27:647–649. 106. Kolb JC, Summers RL, Galli RL. Cervical collar-induced changes in intracranial pressure. Am J Emerg Med. 1999;17:135–137. 107. Mobbs RJ, Stoodley MA, Fuller J. Effect of cervical hard collar on intracranial pressure after head injury. ANZ J Surg. 2002;72:389–391. 108. Wechsler B, Kim H, Hunter J. Trampolines, children, and strokes. Am J Phys Med Rehabil. 2001;80:608–613. 109. Eberle B, Dick WF, Schneider T, Wisser G, Doetsch S, Tzanova I. Checking the carotid pulse check: diagnostic accuracy of first responders in patients with and without a pulse. Resuscitation. 1996;33: 107–116. 110. Bahr J, Klingler H, Panzer W, Rode H, Kettler D. Skills of lay people in checking the carotid pulse. Resuscitation. 1997;35:23–26. 111. Ruppert M, Reith MW, Widmann JH, Lackner CK, Kerkmann R, Schweiberer L, Peter K. Checking for breathing: evaluation of the diagnostic capability of emergency medical services personnel, phy- sicians, medical students, and medical laypersons. Ann Emerg Med. 1999;34:720–729. 112. Safar P, Escarraga LA, Chang F. Upper airway obstruction in the unconscious patient. J Appl Physiol. 1959;14:760–764. 113. Kern KB, Hilwig RW, Berg RA, Sanders AB, Ewy GA. Importance of continuous chest compressions during cardiopulmonary resuscitation: improved outcome during a simulated single lay-rescuer scenario. Cir- culation. 2002;105:645–649. 114. Baskett P, Nolan J, Parr M. Tidal volumes which are perceived to be adequate for resuscitation. Resuscitation. 1996;31:231–234. 115. Aufderheide TP, Sigurdsson G, Pirrallo RG, Yannopoulos D, McKnite S, von Briesen C, Sparks CW, Conrad CJ, Provo TA, Lurie KG. Hyperventilation-induced hypotension during cardiopulmonary resusci- tation. Circulation. 2004;109:1960–1965. 116. Garnett AR, Ornato JP, Gonzalez ER, Johnson EB. End-tidal carbon dioxide monitoring during cardiopulmonary resuscitation. JAMA. 1987; 257:512–515. 117. American Heart Association in collaboration with International Liaison Committee on Resuscitation. Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care: International Con- Part 4: Adult Basic Life Support IV-31 sensus on Science, Part 3: adult basic life support. Circulation. 2000; 102(suppl I):I-22–I-59. 118. Paradis NA, Martin GB, Goetting MG, Rosenberg JM, Rivers EP, Appleton TJ, Nowak RM. Simultaneous aortic, jugular bulb, and right atrial pressures during cardiopulmonary resuscitation in humans: insights into mechanisms. Circulation. 1989;80:361–368. 119. Idris AH, Staples ED, O’Brien DJ, Melker RJ, Rush WJ, Del Duca KD, Falk JL. Effect of ventilation on acid-base balance and oxygenation in low blood-flow states. Crit Care Med. 1994;22:1827–1834. 120. Idris AH, Gabrielli A, Caruso L. Smaller tidal volume is safe and effective for bag-valve-ventilation, but not for mouth-to-mouth venti- lation: an animal model for basic life support [abstract]. Circulation. 1999;100(suppl I):I-644. 121. Idris A, Wenzel V, Banner MJ, Melker RJ. Smaller tidal volumes minimize gastric inflation during CPR with an unprotected airway [abstract]. Circulation. 1995;92(suppl):I-759. 122. Dorph E, Wik L, Steen PA. Arterial blood gases with 700 ml tidal volumes during out-of-hospital CPR. Resuscitation. 2004;61:23–27. 123. Winkler M, Mauritz W, Hackl W, Gilly H, Weindlmayr-Goettel M, Steinbereithner K, Schindler I. Effects of half the tidal volume during cardiopulmonary resuscitation on acid-base balance and haemody- namics in pigs. Eur J Emerg Med. 1998;5:201–206. 124. Dorges V, Ocker H, Hagelberg S, Wenzel V, Idris AH, Schmucker P. Smaller tidal volumes with room-air are not sufficient to ensure adequate oxygenation during bag-valve-mask ventilation. Resuscitation. 2000;44:37–41. 125. Dorges V, Ocker H, Wenzel V, Sauer C, Schmucker P. Emergency airway management by non-anaesthesia house officers–a comparison of three strategies. Emerg Med J. 2001;18:90–94. 126. Bowman FP, Menegazzi JJ, Check BD, Duckett TM. Lower esophageal sphincter pressure during prolonged cardiac arrest and resuscitation. Ann Emerg Med. 1995;26:216–219. 127. Davis K Jr, Johannigman JA, Johnson RC Jr, Branson RD. Lung com- pliance following cardiac arrest [published correction appears in Acad Emerg Med. 1995;2:1115]. Acad Emerg Med. 1995;2:874–878. 128. Wenzel V, Idris AH, Banner MJ, Fuerst RS, Tucker KJ. The compo- sition of gas given by mouth-to-mouth ventilation during CPR. Chest. 1994;106:1806–1810. 129. Mejicano GC, Maki DG. Infections acquired during cardiopulmonary resuscitation: estimating the risk and defining strategies for prevention. Ann Intern Med. 1998;129:813–828. 130. Ornato JP, Hallagan LF, McMahan SB, Peeples EH, Rostafinski AG. Attitudes of BCLS instructors about mouth-to-mouth resuscitation during the AIDS epidemic. Ann Emerg Med. 1990;19:151–156. 131. Brenner BE, Van DC, Cheng D, Lazar EJ. Determinants of reluctance to perform CPR among residents and applicants: the impact of experience on helping behavior. Resuscitation. 1997;35:203–211. 132. Hew P, Brenner B, Kaufman J. Reluctance of paramedics and emergency medical technicians to perform mouth-to-mouth resusci- tation. J Emerg Med. 1997;15:279–284. 133. Terndrup TE, Warner DA. Infant ventilation and oxygenation by basic life support providers: comparison of methods. Prehospital Disaster Med. 1992;7:35–40. 134. Hess D, Ness C, Oppel A, Rhoads K. Evaluation of mouth-to-mask ventilation devices. Respir Care. 1989;34:191–195. 135. Figura N. Mouth-to-mouth resuscitation and Helicobacter pylori infection. Lancet. 1996;347:1342. 136. Heilman KM, Muschenheim C. Primary cutaneous tuberculosis resulting from mouth-to-mouth respiration. N Engl J Med. 1965;273: 1035–1036. 137. Simmons M, Deao D, Moon L, Peters K, Cavanaugh S. Bench eval- uation: three face-shield CPR barrier devices. Respir Care. 1995;40: 618–623. 138. Ruben H. The immediate treatment of respiratory failure. Br J Anaesth. 1964;36:542–549. 139. Bhalla RK, Corrigan A, Roland NJ. Comparison of two face masks used to deliver early ventilation to laryngectomized patients. Ear Nose Throat J. 2004;83:414–416. 140. Barnes TA. Emergency ventilation techniques and related equipment. Respir Care. 1992;37:673–694. 141. Johannigman JA, Branson RD, Davis K Jr, Hurst JM. Techniques of emergency ventilation: a model to evaluate tidal volume, airway pressure, and gastric insufflation. J Trauma. 1991;31:93–98. 142. Elam JO. Bag-valve-mask O 2 ventilation. In: Safar P, Elam JO, eds. Advances in Cardiopulmonary Resuscitation: The Wolf Creek Con- ference on Cardiopulmonary Resuscitation. New York, NY: Springer- Verlag, Inc;1977:73–79. 143. Dailey RH. The Airway: Emergency Management. St Louis, Mo: Mosby Year Book; 1992. 144. Elling R, Politis J. An evaluation of emergency medical technicians’ ability to use manual ventilation devices. Ann Emerg Med. 1983;12: 765–768. 145. Wakeling HG, Butler PJ, Baxter PJC. The laryngeal mask airway: a comparison between two insertion techniques. Anesth Analg. 1997;85: 687–690. 146. Voyagis GS, Photakis D, Kellari A, Kostanti E, Kaklis S, Secha- Dousaitou PN, Tsakiropoulou-Alexiou H. The laryngeal mask airway: a survey of its usage in 1,096 patients. Minerva Anestesiol. 1996;62: 277–280. 147. Baraka A, Salem R. The Combitube oesophageal-tracheal double lumen airway for difficult intubation [letter]. Can J Anaesth. 1993;40: 1222–1223. 148. Frass M, Frenzer R, Rauscha F, Schuster E, Glogar D. Ventilation with the esophageal tracheal combitube in cardiopulmonary resuscitation: promptness and effectiveness. Chest. 1988;93:781–784. 149. Frass M, Rodler S, Frenzer R, Ilias W, Leithner C, Lackner F. Esophageal tracheal combitube, endotracheal airway, and mask: com- parison of ventilatory pressure curves. J Trauma. 1989;29:1476–1479. 150. Dorph E, Wik L, Stromme TA, Eriksen M, Steen PA. Oxygen delivery and return of spontaneous circulation with ventilation:compression ratio 2:30 versus chest compressions only CPR in pigs. Resuscitation. 2004; 60:309–318. 151. Berg RA, Sanders AB, Kern KB, Hilwig RW, Heidenreich JW, Porter ME, Ewy GA. Adverse hemodynamic effects of interrupting chest compressions for rescue breathing during cardiopulmonary resuscitation for ventricular fibrillation cardiac arrest. Circulation. 2001;104: 2465–2470. 152. Sellick BA. Cricoid pressure to control regurgitation of stomach contents during induction of anaesthesia. Lancet. 1961;2:404–406. 153. Petito SP, Russell WJ. The prevention of gastric inflation—a neglected benefit of cricoid pressure. Anaesth Intensive Care. 1988;16:139–143. 154. Perkins GD, Stephenson B, Hulme J, Monsieurs KG. Birmingham assessment of breathing study (BABS). Resuscitation. 2005;64: 109–113. 155. Moule P. Checking the carotid pulse: diagnostic accuracy in students of the healthcare professions. Resuscitation. 2000;44:195–201. 156. Stiell I, Nichol G, Wells G, De Maio V, Nesbitt L, Blackburn J, Spaite D, Group OS. Health-related quality of life is better for cardiac arrest survivors who received citizen cardiopulmonary resuscitation. Circu- lation. 2003;108:1939–1944. 157. International Liaison Committee on Resuscitation. 2005 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardio- vascular Care Science With Treatment Recommendations. Circulation. 2005;112:III-1–III-136. 158. Kouwenhoven WB, Jude JR, Knickerbocker GG. Closed-chest cardiac massage. JAMA. 1960;173:1064–1067. 159. Handley AJ, Handley JA. Performing chest compressions in a confined space. Resuscitation. 2004;61:55–61. 160. Perkins GD, Stephenson BT, Smith CM, Gao F. A comparison between over-the-head and standard cardiopulmonary resuscitation. Resusci- tation. 2004;61:155–161. 161. Perkins GD, Benny R, Giles S, Gao F, Tweed MJ. Do different mat- tresses affect the quality of cardiopulmonary resuscitation? Intensive Care Med. 2003;29:2330–2335. 162. Tweed M, Tweed C, Perkins GD. The effect of differing support surfaces on the efficacy of chest compressions using a resuscitation manikin model. Resuscitation. 2001;51:179–183. 163. Handley AJ. Teaching hand placement for chest compression–a simpler technique. Resuscitation. 2002;53:29–36. 164. Liberman M, Lavoie A, Mulder D, Sampalis J. Cardiopulmonary resus- citation: errors made by pre-hospital emergency medical personnel. Resuscitation. 1999;42:47–55. 165. Kundra P, Dey S, Ravishankar M. Role of dominant hand position during external cardiac compression. Br J Anaesth. 2000;84:491–493. 166. Aufderheide TP, Pirrallo RG, Yannopoulos D, Klein JP, von Briesen C, Sparks CW, Deja KA, Conrad CJ, Kitscha DJ, Provo TA, Lurie KG. Incomplete chest wall decompression: a clinical evaluation of CPR performance by EMS personnel and assessment of alternative manual chest compression-decompression techniques. Resuscitation. 2005;64: 353–362. 167. Yannopoulos D, McKnite S, Aufderheide TP, Sigurdsson G, Pirrallo RG, Benditt D, Lurie KG. Effects of incomplete chest wall decom- pression during cardiopulmonary resuscitation on coronary and cerebral perfusion pressures in a porcine model of cardiac arrest. Resuscitation. 2005;64:363–372. 168. Handley AJ, Handley JA. The relationship between rate of chest com- pression and compression:relaxation ratio. Resuscitation. 1995;30: 237–241. IV-32 Circulation December 13, 2005 169. Fitzgerald KR, Babbs CF, Frissora HA, Davis RW, Silver DI. Cardiac output during cardiopulmonary resuscitation at various compression rates and durations. Am J Physiol. 1981;241:H442–H448. 170. Halperin HR, Tsitlik JE, Guerci AD, Mellits ED, Levin HR, Shi AY, Chandra N, Weisfeldt ML. Determinants of blood flow to vital organs during cardiopulmonary resuscitation in dogs. Circulation. 1986;73: 539–550. 171. Swart GL, Mateer JR, DeBehnke DJ, Jameson SJ, Osborn JL. The effect of compression duration on hemodynamics during mechanical high- impulse CPR. Acad Emerg Med. 1994;1:430–437. 172. Wik L, Kramer-Johansen J, Myklebust H, Sorebo H, Svensson L, Fellows B, Steen PA. Quality of cardiopulmonary resuscitation during out-of-hospital cardiac arrest. JAMA. 2005;293:299–304. 173. Abella BS, Alvarado JP, Myklebust H, Edelson DP, Barry A, O’Hearn N, Vanden Hoek TL, Becker LB. Quality of cardiopulmonary resusci- tation during in-hospital cardiac arrest. JAMA. 2005;293:305–310. 174. Yu T, Weil MH, Tang W, Sun S, Klouche K, Povoas H, Bisera J. Adverse outcomes of interrupted precordial compression during automated defibrillation. Circulation. 2002;106:368–372. 175. Swenson RD, Weaver WD, Niskanen RA, Martin J, Dahlberg S. He- modynamics in humans during conventional and experimental methods of cardiopulmonary resuscitation. Circulation. 1988;78:630–639. 176. Kern KB, Sanders AB, Raife J, Milander MM, Otto CW, Ewy GA. A study of chest compression rates during cardiopulmonary resuscitation in humans: the importance of rate-directed chest compressions. Arch Intern Med. 1992;152:145–149. 177. Abella BS, Sandbo N, Vassilatos P, Alvarado JP, O’Hearn N, Wigder HN, Hoffman P, Tynus K, Vanden Hoek TL, Becker LB. Chest com- pression rates during cardiopulmonary resuscitation are suboptimal: a prospective study during in-hospital cardiac arrest. Circulation. 2005; 111:428–434. 178. Berg RA, Cobb LA, Doherty A, Ewy GA, Gerardi MJ, Handley AJ, Kinney S, Phillips B, Sanders A, Wyllie J. Chest compressions and basic life support-defibrillation. Ann Emerg Med. 2001;37:S26–S35. 179. Berg RA, Hilwig RW, Kern KB, Sanders AB, Xavier LC, Ewy GA. Automated external defibrillation versus manual defibrillation for pro- longed ventricular fibrillation: lethal delays of chest compressions before and after countershocks. Ann Emerg Med. 2003;42:458–467. 180. Berg RA, Hilwig RW, Kern KB, Ewy GA. “Bystander” chest com- pressions and assisted ventilation independently improve outcome from piglet asphyxial pulseless “cardiac arrest.” Circulation. 2000;101: 1743–1748. 181. Berg RA, Kern KB, Hilwig RW, Ewy GA. Assisted ventilation during ’bystander’ CPR in a swine acute myocardial infarction model does not improve outcome. Circulation. 1997;96:4364–4371. 182. Greingor JL. Quality of cardiac massage with ratio compression- ventilation 5/1 and 15/2. Resuscitation. 2002;55:263–267. 183. Feneley MP, Maier GW, Kern KB, Gaynor JW, Gall SA Jr, Sanders AB, Raessler K, Muhlbaier LH, Rankin JS, Ewy GA. Influence of com- pression rate on initial success of resuscitation and 24 hour survival after prolonged manual cardiopulmonary resuscitation in dogs. Circulation. 1988;77:240–250. 184. Ochoa FJ, Ramalle-Gomara E, Carpintero JM, Garcia A, Saralegui I. Competence of health professionals to check the carotid pulse. Resus- citation. 1998;37:173–175. 185. Babbs CF, Kern KB. Optimum compression to ventilation ratios in CPR under realistic, practical conditions: a physiological and mathematical analysis. Resuscitation. 2002;54:147–157. 186. Berg RA, Kern KB, Hilwig RW, Berg MD, Sanders AB, Otto CW, Ewy GA. Assisted ventilation does not improve outcome in a porcine model of single-rescuer bystander cardiopulmonary resuscitation. Circulation. 1997;95:1635–1641. 187. Berg RA, Kern KB, Hilwig RW, Ewy GA. Assisted ventilation during ‘bystander’ CPR in a swine acute myocardial infarction model does not improve outcome. Circulation. 1997;96:4364–4371. 188. Kern KB, Hilwig RW, Berg RA, Ewy GA. Efficacy of chest compression-only BLS CPR in the presence of an occluded airway. Resuscitation. 1998;39:179–188. 189. Berg RA, Sanders AB, Milander M, Tellez D, Liu P, Beyda D. Efficacy of audio-prompted rate guidance in improving resuscitator performance of cardiopulmonary resuscitation on children. Acad Emerg Med. 1994; 1:35–40. 190. Barsan WG. Experimental design for study of cardiopulmonary resus- citation in dogs. Ann Emerg Med. 1981;10:135–137. 191. Milander MM, Hiscok PS, Sanders AB, Kern KB, Berg RA, Ewy GA. Chest compression and ventilation rates during cardiopulmonary resus- citation: the effects of audible tone guidance. Acad Emerg Med. 1995; 2:708–713. 192. Thomas SH, Stone CK, Austin PE, March JA, Brinkley S. Utilization of a pressure-sensing monitor to improve in-flight chest compressions. Am J Emerg Med. 1995;13:155–157. 193. Wik L, Thowsen J, Steen PA. An automated voice advisory manikin system for training in basic life support without an instructor: a novel approach to CPR training. Resuscitation. 2001;50:167–172. 194. Elding C, Baskett P, Hughes A. The study of the effectiveness of chest compressions using the CPR-plus. Resuscitation. 1998;36:169–173. 195. Handley AJ, Handley SA. Improving CPR performance using an audible feedback system suitable for incorporation into an automated external defibrillator. Resuscitation. 2003;57:57–62. 196. Wik L, Myklebust H, Auestad BH, Steen PA. Retention of basic life support skills 6 months after training with an automated voice advisory manikin system without instructor involvement. Resuscitation. 2002;52: 273–279. 197. Berg RA, Kern KB, Sanders AB, Otto CW, Hilwig RW, Ewy GA. Bystander cardiopulmonary resuscitation: is ventilation necessary? Cir- culation. 1993;88:1907–1915. 198. Chandra NC, Gruben KG, Tsitlik JE, Brower R, Guerci AD, Halperin HH, Weisfeldt ML, Permutt S. Observations of ventilation during resus- citation in a canine model. Circulation. 1994;90:3070–3075. 199. Tang W, Weil MH, Sun S, Kette D, Gazmuri RJ, O’Connell F, Bisera J. Cardiopulmonary resuscitation by precordial compression but without mechanical ventilation. Am J Respir Crit Care Med. 1994;150: 1709–1713. 200. Berg RA, Wilcoxson D, Hilwig RW, Kern KB, Sanders AB, Otto CW, Eklund DK, Ewy GA. The need for ventilatory support during bystander CPR. Ann Emerg Med. 1995;26:342–350. 201. Becker LB, Berg RA, Pepe PE, Idris AH, Aufderheide TP, Barnes TA, Stratton SJ, Chandra NC. A reappraisal of mouth-to-mouth ventilation during bystander-initiated cardiopulmonary resuscitation. A statement for healthcare professionals from the Ventilation Working Group of the Basic Life Support and Pediatric Life Support Subcommittees, American Heart Association. Resuscitation. 1997;35:189–201. 202. Sirbaugh PE, Pepe PE, Shook JE, Kimball KT, Goldman MJ, Ward MA, Mann DM. A prospective, population-based study of the demographics, epidemiology, management, and outcome of out-of-hospital pediatric cardiopulmonary arrest [published correction appears in Ann Emerg Med. 1999;33:358]. Ann Emerg Med. 1999;33:174–184. 203. Waalewijn RA, Tijssen JGP, Koster RW. Bystander initiated actions in out-of-hospital cardiopulmonary resuscitation: results from the Amsterdam Resuscitation Study (ARREST).Resuscitation. 2001;50: 273–279. 204. Van Hoeyweghen RJ, Bossaert LL, Mullie A, Calle P, Martens P, Buylaert WA, Delooz H. Quality and efficiency of bystander CPR. Belgian Cerebral Resuscitation Study Group. Resuscitation. 1993;26: 47–52. 205. Berg RA, Hilwig RW, Kern KB, Babar I, Ewy GA. Simulated mouth- to-mouth ventilation and chest compressions (bystander cardiopulmo- nary resuscitation) improves outcome in a swine model of prehospital pediatric asphyxial cardiac arrest. Crit Care Med. 1999;27:1893–1899. 206. Berg RA. Role of mouth-to-mouth rescue breathing in bystander car- diopulmonary resuscitation for asphyxial cardiac arrest. Crit Care Med. 2000;28(suppl):N193–N195. 207. Hallstrom AP. Dispatcher-assisted “phone” cardiopulmonary resusci- tation by chest compression alone or with mouth-to-mouth ventilation. Crit Care Med. 2000;28:N190–N192. 208. Weil MH, Rackow EC, Trevino R, Grundler W, Falk JL, Griffel MI. Difference in acid-base state between venous and arterial blood during cardiopulmonary resuscitation. N Engl J Med. 1986;315:153–156. 209. Sanders AB, Otto CW, Kern KB, Rogers JN, Perrault P, Ewy GA. Acid-base balance in a canine model of cardiac arrest. Ann Emerg Med. 1988;17:667–671. 210. Criley JM, Blaufuss AH, Kissel GL. Cough-induced cardiac com- pression: self-administered from of cardiopulmonary resuscitation. JAMA. 1976;236:1246–1250. 211. Niemann JT, Rosborough JP, Niskanen RA, Alferness C, Criley JM. Mechanical “cough” cardiopulmonary resuscitation during cardiac arrest in dogs. Am J Cardiol. 1985;55:199–204. 212. Miller B, Cohen A, Serio A, Bettock D. Hemodynamics of cough cardiopulmonary resuscitation in a patient with sustained torsades de pointes/ventricular flutter. J Emerg Med. 1994;12:627–632. 213. Rieser MJ. The use of cough-CPR in patients with acute myocardial infarction. J Emerg Med. 1992;10:291–293. 214. Miller B, Lesnefsky E, Heyborne T, Schmidt B, Freeman K, Breck- inridge S, Kelley K, Mann D, Reiter M. Cough-cardiopulmonary resus- citation in the cardiac catheterization laboratory: hemodynamics during an episode of prolonged hypotensive ventricular tachycardia. Cathet Cardiovasc Diagn. 1989;18:168–171. Part 4: Adult Basic Life Support IV-33 215. Bircher N, Safar P, Eshel G, Stezoski W. Cerebral and hemodynamic variables during cough-induced CPR in dogs. Crit Care Med. 1982;10: 104–107. 216. Saba SE, David SW. Sustained consciousness during ventricular fibril- lation: case report of cough cardiopulmonary resuscitation. Cathet Car- diovasc Diagn. 1996;37:47–48. 217. Mazer SP, Weisfeldt M, Bai D, Cardinale C, Arora R, Ma C, Sciacca RR, Chong D, Rabbani LE. Reverse CPR: a pilot study of CPR in the prone position. Resuscitation. 2003;57:279–285. 218. Sun WZ, Huang FY, Kung KL, Fan SZ, Chen TL. Successful cardiopul- monary resuscitation of two patients in the prone position using reversed precordial compression. Anesthesiology. 1992;77:202–204. 219. Tobias JD, Mencio GA, Atwood R, Gurwitz GS. Intraoperative cardio- pulmonary resuscitation in the prone position. J Pediatr Surg. 1994;29: 1537–1538. 220. Brown J, Rogers J, Soar J. Cardiac arrest during surgery and ventilation in the prone position: a case report and systematic review. Resuscitation. 2001;50:233–238. 221. Jacobs IG, Finn JC, Oxer HF, Jelinek GA. CPR before defibrillation in out-of-hospital cardiac arrest: a randomized trial. Emerg Med Australas. 2005;17:39–45. 222. Perkins GD. In-water resuscitation: a pilot evaluation. Resuscitation. 2005;65:321–324. 223. March NF, Matthews RC. New techniques in external cardiac com- pressions: aquatic cardiopulmonary resuscitation. JAMA. 1980;244: 1229–1232. 224. Rosen P, Stoto M, Harley J. The use of the Heimlich maneuver in near-drowning: Institute of Medicine report. J Emerg Med. 1995;13: 397–405. 225. Watson RS, Cummings P, Quan L, Bratton S, Weiss NS. Cervical spine injuries among submersion victims. J Trauma. 2001;51:658–662. 226. Kewalramani LS, Kraus JF. Acute spinal-cord lesions from diving–epi- demiological and clinical features. West J Med. 1977;126:353–361. 227. Hwang V, Shofer FS, Durbin DR, Baren JM. Prevalence of traumatic injuries in drowning and near drowning in children and adolescents. Arch Pediatr Adolesc Med. 2003;157:50–53. 228. Green BA, Gabrielsen MA, Hall WJ, O’Heir J. Analysis of swimming pool accidents resulting in spinal cord injury. Paraplegia. 1980;18: 94–100. 229. Good RP, Nickel VL. Cervical spine injuries resulting from water sports. Spine. 1980;5:502–506. 230. Goh SH, Low BY. Drowning and near-drowning–some lessons learnt. Ann Acad Med Singapore. 1999;28:183–188. 231. Branche CM, Sniezek JE, Sattin RW, Mirkin IR. Water recreation- related spinal injuries: risk factors in natural bodies of water. Accid Anal Prev. 1991;23:13–17. 232. Handley AJ. Recovery position. Resuscitation. 1993;26:93–95. 233. Turner S, Turner I, Chapman D, Howard P, Champion P, Hatfield J, James A, Marshall S, Barber S. A comparative study of the 1992 and 1997 recovery positions for use in the UK. Resuscitation. 1998;39: 153–160. 234. Fulstow R, Smith GB. The new recovery position, a cautionary tale. Resuscitation. 1993;26:89–91. 235. Rathgeber J, Panzer W, Gunther U, Scholz M, Hoeft A, Bahr J, Kettler D. Influence of different types of recovery positions on perfusion indices of the forearm. Resuscitation. 1996;32:13–17. 236. Gunn BD, Eizenberg N, Silberstein M, McMeeken JM, Tully EA, Stillman BC, Brown DJ, Gutteridge GA. How should an unconscious person with a suspected neck injury be positioned? Prehosp Disaster Med. 1995;10:239–244. 237. Blake WE, Stillman BC, Eizenberg N, Briggs C, McMeeken JM. The position of the spine in the recovery position–an experimental com- parison between the lateral recovery position and the modified HAINES position. Resuscitation. 2002;53:289–297. 238. Fingerhut LA, Cox CS, Warner M. International comparative analysis of injury mortality: findings from the ICE on injury statistics. International Collaborative Effort on Injury Statistics. Adv Data. 1998:1–20. 239. Redding JS. The choking controversy: critique of evidence on the Heimlich maneuver. Crit Care Med. 1979;7:475–479. 240. Vilke GM, Smith AM, Ray LU, Steen PJ, Murrin PA, Chan TC. Airway obstruction in children aged less than 5 years: the prehospital expe- rience. Prehosp Emerg Care. 2004;8:196–199. 241. Ingalls TH. Heimlich versus a slap on the back. N Engl J Med. 1979; 300:990. 242. Heimlich HJ. First aid for choking children: back blows and chest thrusts cause complications and death. Pediatrics. 1982;70:120–125. 243. Heimlich HJ. A life-saving maneuver to prevent food choking. JAMA. 1975;234:398–401. 244. Heimlich HJ, Hoffmann KA, Canestri FR. Food-choking and drowning deaths prevented by external subdiaphragmatic compression: physiolog- ical basis. Ann Thorac Surg. 1975;20:188–195. 245. Nelson KR. Heimlich maneuver for esophageal obstruction. N Engl J Med. 1989;320:1016. 246. Penny RW. The Heimlich manoeuvre. BMJ (Clin Res Ed). 1983;286: 1145–1146. 247. Lapostolle F, Desmaizieres M, Adnet F, Minadeo J. Telephone-assisted Heimlich maneuver. Ann Emerg Med. 2000;36:171. 248. Skulberg A. Chest compression–an alternative to the Heimlich manoeuver? [letter]. Resuscitation. 1992;24:91. 249. Heimlich HJ. Death from food-choking prevented by a new life-saving maneuver. Heart Lung. 1976;5:755–758. 250. Brauner DJ. The Heimlich maneuver: procedure of choice? J Am Geriatr Soc. 1987;35:78. 251. Gallardo A, Rosado R, Ramirez D, Medina P, Mezquita S, Sanchez J. Rupture of the lesser gastric curvature after a Heimlich maneuver. Surg Endosc. 2003;17:1495. 252. Ayerdi J, Gupta SK, Sampson LN, Deshmukh N. Acute abdominal aortic thrombosis following the Heimlich maneuver. Cardiovasc Surg. 2002;10:154–156. 253. Tung PH, Law S, Chu KM, Law WL, Wong J. Gastric rupture after Heimlich maneuver and cardiopulmonary resuscitation. Hepatogastro- enterology. 2001;48:109–111. 254. Majumdar A, Sedman PC. Gastric rupture secondary to successful Heimlich manoeuvre. Postgrad Med J. 1998;74:609–610. 255. Bintz M, Cogbill TH. Gastric rupture after the Heimlich maneuver. J Trauma. 1996;40:159–160. 256. Dupre MW, Silva E, Brotman S. Traumatic rupture of the stomach secondary to Heimlich maneuver. Am J Emerg Med. 1993;11:611–612. 257. van der Ham AC, Lange JF. Traumatic rupture of the stomach after Heimlich maneuver. J Emerg Med. 1990;8:713–715. 258. Cowan M, Bardole J, Dlesk A. Perforated stomach following the Heimlich maneuver. Am J Emerg Med. 1987;5:121–122. 259. Croom DW. Rupture of stomach after attempted Heimlich maneuver. JAMA. 1983;250:2602–2603. 260. Visintine RE, Baick CH. Ruptured stomach after Heimlich maneuver. JAMA. 1975;234:415. 261. Mack L, Forbes TL, Harris KA. Acute aortic thrombosis following incorrect application of the Heimlich maneuver. Ann Vasc Surg. 2002; 16:130–133. 262. Roehm EF, Twiest MW, Williams RC Jr. Abdominal aortic thrombosis in association with an attempted Heimlich maneuver. JAMA. 1983;249: 1186–1187. 263. Kirshner RL, Green RM. Acute thrombosis of abdominal aortic aneu- rysm subsequent to Heimlich maneuver: a case report. J Vasc Surg. 1985;2:594–596. 264. Rakotoharinandrasana H, Petit E, Dumas P, Vandermarcq P, Gil R, Neau JP. [Internal carotid artery dissection after Heimlich maneuver]. Ann Fr Anesth Reanim. 2003;22:43–45. 265. Wolf DA. Heimlich trauma: a violent maneuver. Am J Forensic Med Pathol. 2001;22:65–67. 266. Valero V. Mesenteric laceration complicating a Heimlich maneuver. Ann Emerg Med. 1986;15:105–106. 267. Ujjin V, Ratanasit S, Nagendran T. Diaphragmatic hernia as a compli- cation of the Heimlich maneuver. Int Surg. 1984;69:175–176. 268. Rich GH. Pneumomediastinum following the Heimlich maneuver. Ann Emerg Med. 1980;9:279–280. 269. Agia GA, Hurst DJ. Pneumomediastinum following the Heimlich maneuver. JACEP. 1979;8:473–475. 270. Meredith MJ, Liebowitz R. Rupture of the esophagus caused by the Heimlich maneuver. Ann Emerg Med. 1986;15:106–107. 271. Chapman JH, Menapace FJ, Howell RR. Ruptured aortic valve cusp: a complication of the Heimlich maneuver. Ann Emerg Med. 1983;12: 446–448. 272. Orlowski JP. Vomiting as a complication of the Heimlich maneuver. JAMA. 1987;258:512–513. 273. Langhelle A, Sunde K, Wik L, Steen PA. Airway pressure with chest compressions versus Heimlich manoeuvre in recently dead adults with complete airway obstruction. Resuscitation. 2000;44:105–108. 274. Guildner CW, Williams D, Subitch T. Airway obstructed by foreign material: the Heimlich maneuver. JACEP. 1976;5:675–677. 275. Ruben H, Macnaughton FI. The treatment of food-choking. Practitioner. 1978;221:725–729. 276. Hartrey R, Bingham RM. Pharyngeal trauma as a result of blind finger sweeps in the choking child. J Accid Emerg Med. 1995;12:52–54. 277. Kabbani M, Goodwin SR. Traumatic epiglottis following blind finger sweep to remove a pharyngeal foreign body. Clin Pediatr (Phila). 1995;34:495–497. IV-34 Circulation December 13, 2005