absorption of Amadori compounds 280 of calcium 103 of copper 117, 127¨C33 of iron 105 of Maillard reaction products 280¨C1 of melanoidins 281 of minerals 98¨C9, 103, 105, 108 of vitamin C 62 of zinc 108 advertising functional foods 310¨C11 nutrition claims 147 Aeromonas species of bacteria 354, 355 alcohol consumption 9, 69 allergens 447¨C8 Alzheimer¡¯s disease 82 Amadori rearrangement products (ARPs) 266¨C9, 280 amine oxidases 119 amino acids 271, 273 cross-linked 277¨C80 amino-carbalines 282¨C3 amino-imidazo-azaarenes (AIAs) 283 anaemia 78, 99, 106, 228 anaerobic respiration 346 analytical systems see functionality testing anti-freeze peptides 339 anti-mutagenic compounds 446 antinutrients 197, 324¨C5 antioxidants 42, 52¨C4, 63¨C4, 281, 294 ascorbic acid 62, 258¨C9, 297, 322¨C3 and high pressure processing 437, 440 and irradiation 382 see also vitamin C Asian communities 47, 51 atherosclerosis 178 b-carbolines 283 b-carotene 35, 39¨C40, 42¨C6, 64¨C5, 250¨C1, 358¨C9 backcross programmes 197 bacteria 350¨C4, 373, 411 bakery products 427¨C30 beriberi 66¨C9 bioactivity 53, 57¨C9, 168¨C9 bioavailability of nutrients 169, 201¨C2 in cereal foods 302¨C3 copper 128¨C9 folates 71 iron 130, 228 minerals 323¨C4 vitamin A 38 bioefficacy of vitamin A 38¨C9 biogenic amines 236 biomarkers 171¨C2, 174¨C5, 181 biotin 37, 80¨C1, 257 and irradiation 380, 381¨C2 blanching 334¨C5, 338, 415¨C16 and vitamin loss 260¨C1 Index Index 475 blood clotting 57¨C8, 59 blood glucose 170, 174¨C5 bone health and meat 235 osteoporosis 50¨C1, 60, 103¨C4 and vitamin D 50¨C1 and vitamin K 58¨C9, 60¨C1 caeruloplasmin 119 calciferol 46, 48¨C50 and irradiation 382¨C3 see also vitamin D calcium 50, 58¨C9, 98, 102¨C5 absorption 103 food sources 104 reference nutrient intake 104 safe intake 105 CALEUR study 21 calorific information 155 Campylobacter 373 cancer 9, 18¨C19, 44, 209 and antioxidants 52 and b-carotene 42¨C4 colon cancer 51, 211¨C14 and meat eating 210, 211¨C14 carbohydrates 154, 173¨C4, 175, 306¨C8 and continuous-flow heat processing 469¨C70 and extrusion cooking 317¨C19 and irradiation 383 carbon dioxide 343¨C5, 346¨C7 cardiovascular disease (CVD) see heart disease carnitine 236 carnosine 236 carotenoids b-carotene 35, 39¨C40, 42¨C6, 64¨C5, 250¨C1, 358¨C9 and high pressure processing 440¨C1 and irradiation 380 and modified atmosphere packaging 358¨C9 catechol oxidase 119 cell differentiation 40 cellular growth 51 cereal foods 22, 102, 166, 185¨C6, 301¨C11 bioavailability of nutrients 302¨C3 mechanical processing 302¨C5 nutritional significance 302¨C3 nutritionally enhanced 308¨C11 thermal processing 303, 305¨C8 cholesterol 198¨C200, 214¨C15, 223, 296, 320 LDL-cholesterol oxidation 54 choline 236 Clostridium botulinum 351 cobalamins 77¨C80, 257 deficiency diseases 78¨C9 food sources 37, 77 and irradiation 380, 381¨C2 toxicity 80 Codex Alimentarius 388, 389¨C90 coeliac disease 48 cold spots 411¨C12, 419 colon cancer 51, 211¨C14 colonic bulk 181 colour of foods 276¨C7, 345 conjugated linoleic acid (CLA) 221¨C3 consumers food choice factors 149, 150¨C1, 168 improving consumer confidence 168 understanding of labelling 149¨C56 continuous-flow heat processing 462¨C72 and carbohydrates 469¨C70 commercialisation 471¨C2 and fats 469¨C70 flash-cooling 466 food quality 466¨C8 heat exchanger selection 464¨C6 and proteins 468¨C9 steam infusion 465 steam injection 465 streamline flow 468 technical problems 472 thermal degradation kinetics 463¨C4 time-temperature profile 466¨C7 turbulent flow 468 and vitamins 470¨C1 copper 65, 117¨C35 absorption 117, 127¨C33 bioavailability 128¨C9 deficiency diseases 117, 121¨C2 distribution in the body 131 in drinking water 123 food sources 120¨C1 function of cuproenzymes 118¨C20 functional copper status 127 and heart disease 122 intake assessment 124¨C7 putative indicators 125¨C6 reference nutrient intake 120 serum copper 125¨C6 toxicity 117, 122¨C4 coronary heart disease (CHD) see heart disease cross-linked amino acids 277¨C80 476 Index cuproenzymes 118¨C20 cyanocobalamin 380, 381¨C2 cytochrome-c oxidase 118 DAFNE (DAta Food NEtworking) project 11, 17¨C18 dairy products 128, 446, 447 data sources 7, 10¨C22 European surveys 13¨C22 food balance sheets (FBS) 10, 22 food frequency questionnaires 13 household budget surveys (HBS) 11¨C12, 17¨C18 individual dietary surveys (IDSs) 12¨C13 deep frying 293, 298 dehydration, and vitamin loss 262 dephytinisation 130 diabetes 48, 172, 174¨C5, 178 diacylglycerols 294 diamine oxidase 119 diet data sources 7, 10¨C22 European dietary patterns 22¨C8 Mediterranean countries 25, 28¨C9, 196, 213 and health 8¨C10 nutrition and the elderly 20¨C1 dietary reference values 34¨C5 digestibility of food 446¨C7 disease-nutrient interactions 63¨C5 DNA damage and repair 56 dopamine b-hydroxylase (DbM) 119 drinking water 123 drip loss 333, 336 elderly people 20¨C1, 47¨C8 and antioxidant vitamins 64 immune system 55¨C6 electrolysis 416 electromagnetic radiation 397 electrons 374¨C5, 377 embryogenesis 41 end-points 171, 174, 181 energy information provision 155 value calculations 146 enhanced diffusion 415¨C16 enhancement see nutritional enhancement enzymes 320 cuproenzymes 118¨C20 xenobiotic enzymes 281¨C2 see also Maillard reaction equilibrium modified atmosphere packaging (EMAP) 347¨C50 Escherichia coli 373, 386, 390 Euronut-SENECA study 20¨C1, 28 European dietary patterns 22¨C8 Mediterranean countries 25, 28¨C9, 196, 213 European Prospective Investigation into Cancer and Nutrition (EPIC) 18¨C19, 28 European surveys 13¨C22 extrusion cooking 314¨C26 and antinutrients 324¨C5 and carbohydrates 317¨C19 future trends 325¨C6 and lipids 321 Maillard reactions 320 and minerals 323¨C4 and phenolic compounds 325 and phytohormones 325 and proteins 320¨C1 and thiamin 323 vitamin stability 321¨C3 wet extrusion 316¨C17 faecal bulk 171, 180¨C6 fats and continuous-flow heat processing 469¨C70 and frying 293 information provision 153, 154 in meat 214¨C23, 234 fatty acids 217¨C22 and cholesterol 223 conjugated linoleic acid (CLA) 221¨C3 monounsaturated fatty acids 218 polyunsaturated fatty acids 219¨C21 saturated fatty acids 218 trans-fatty acids 222 ferroxidases 119 fibre 155, 166, 181¨C2, 309, 319 fish freezing 336¨C7 high pressure processing 443¨C4 trimethylamineoxide reduction 345¨C6 flash-cooling 466 flavonoids 202 flour production 304¨C5 fluoride 98 folates 70¨C7, 202¨C3, 256 bioavailability 71 Index 477 and cardiovascular disease (CVD) 75¨C6 deficiency effects 76 food sources 37, 70¨C1 fortification of foods 74¨C5, 77 reference nutrient intake 36, 72, 74 requirements 72¨C5 toxicity 76¨C7 food balance sheets (FBS) 10, 22 food frequency questionnaires 13 food matrix properties 170 Food Standards Agency (FSA) 160¨C1 fortification 195, 202¨C3 with folates 74¨C5, 77 with minerals 102, 324 see also nutritional enhancement fractures see bone health freezing 331¨C40 anti-freeze peptides 339 drip loss 333, 336 fruit 333¨C6 ¡®glassy state¡¯ freezing 338¨C9 meat and fish 336¨C7 Ostwald ripening 333 quality and nutrient loss 332¨C3 vegetables and fruit 333¨C6 and vitamin loss 261 fruit availability 24, 25 and cancer protection 44, 65 and cardiovascular disease 65, 75¨C6 cooking methods 335¨C6 high pressure processing 446 modified atmosphere packaging 356¨C62 storage after harvest 334 washing and blanching 334¨C5, 338 frying 293¨C8 deep frying 293, 298 and fat consumption 293 frying oil 294¨C5, 298 impact on nutrients 296¨C7 meat 428¨C30 sensory characteristics 297¨C8 shallow frying 293 FSA (Food Standards Agency) 160¨C1 functional foods market for 186¨C7 marketing 310¨C11 functionality testing biomarkers 171¨C2, 174¨C5, 181 data limitations 168¨C9, 173¨C4 end-points 171, 174, 181 extrapolation between products 167 food matrix properties 170 food processing and nutritional quality 165¨C7 future trends 186¨C8 glycaemic-glucose equivalents 174¨C80 indices 172¨C3 faecal bulking index 180¨C6 glycaemic index (GI) 173, 175¨C9 market for functional foods 186¨C7 types of tests 167 validation of tests 172 wheat bran equivalents 180¨C6 gamma rays 374, 375 genetic engineering 197¨C8, 200¨C1, 204¨C6 ¡®glassy state¡¯ freezing 338¨C9 glucosinolates 325, 361¨C2 glutathione 236 glycaemic index (GI) 173, 175¨C9, 307 glycaemic-glucose equivalents 174¨C80 goitre 99, 111, 196 Grasbeck-Immerslund syndrome 78 Guideline Daily Amounts (GDAs) 158¨C9 haemorrhagic disease of the newborn (HDN) 59¨C60 hair colour 82 haptocorrins 78 heart disease cardiovascular disease 8¨C9, 20, 75¨C6, 122 and copper deficiency 122 coronary heart disease 9, 20, 53¨C5 vascular cell dysfunction 56 and vitamin E 53¨C5 heat exchangers 464¨C6 heat processing see thermal processing hephaestin 131 heterocyclic amines (HAs) 282¨C5 high pressure processing 433¨C61 and allergens 447¨C8 anti-mutagenic compounds 446 and ascorbic acid 437, 440 and carotene 440¨C1 commercial food products 436, 438¨C9 dairy products 446, 447 digestibility of food 446¨C7 equipment 435¨C6 fish products 443¨C4 food quality 433¨C4 478 Index fruit 446 future trends 448 and lipids 442¨C5 meat products 444¨C5 and mineral content 445¨C6 and retinol 441 safety 434¨C5 and sweeteners 445 vegetables 446 and vitamins 437¨C42 histidinoalanine (HAL) 278¨C9, 279¨C80 homocysteine 72, 75¨C6, 80, 84¨C5 household budget surveys (HBS) 11¨C12, 17¨C18 Hox family genes 41 hunter-gatherer diets 227 hydroperoxides 294¨C5, 384 hyperglycaemia 174 hypervitaminosis A 44¨C5 immune system and elderly people 55¨C6 and vitamin A 41¨C2, 43 and vitamin C 65¨C6 and vitamin D 51¨C2 and vitamin E 55¨C6 and zinc deficiency 109 Indian Childhood Cirrhosis (ICC) 124 indices 172¨C3 faecal bulking index 180¨C6 glycaemic index (GI) 173, 175¨C9 individual dietary surveys (IDSs) 12¨C13 infants, haemorrhagic disease of the newborn (HDN) 59¨C60 information panels 151¨C6 infrared heating 398, 423¨C31 bakery products 427¨C30 food industry applications 426¨C7 food quality 428¨C30 frying meat 428¨C30 future trends 430¨C1 near infrared heating (NIR) 424 nutritional quality 430 penetration depths 426 iodine 98, 99, 102, 111 deficiency disorders 8, 196 ionising radiation see irradiation iron 64¨C5, 98, 99, 105¨C7 absorption 105 bioavailability 130, 228 deficiency diseases 228 food sources 107 iron/vitamin C reaction 64 in meat 228¨C30, 235 reference nutrient intake 106¨C7 safe intake 107 irradiation 371¨C92 and ascorbic acid 382 benefits 385¨C6 and biotin 380, 381¨C2 and calciferol 382¨C3 and carbohydrates 383 and carotenoids 380 and cobalamins 381¨C2 consumer attitudes to 386¨C9 and cyanocobalamin 380, 381¨C2 effect on food 377¨C8 future trends 390¨C1 history of 372¨C3 and lipids 383¨C4 and niacin 380, 381¨C2 nutritional adequacy 379¨C80 principles of 373¨C7 and proteins 384 and pyridoxine 380, 381¨C2 regulation of 386¨C90 and riboflavin 380, 381¨C2 safety of 378¨C9, 385 and thiamin 380, 381¨C2 and tocopherols 383 and vitamins 262, 380¨C3 wholesomeness of irradiated food 384¨C5 isotope studies 132¨C3 Keshan disease 112 Korsakoff syndrome 69 labelling 142¨C63 consumer understanding of 149¨C56 future trends in 161¨C3 Guideline Daily Amounts (GDAs) 158¨C9 legibility 160 nutrition information panels 151¨C6 Nutrition Labelling Directive 144¨C9 research findings 157¨C61 retailer influence on 149¨C50 LDL-cholesterol oxidation 54 legislation see regulation lipids 24¨C5, 297 extrusion cooking 321 high pressure processing 442¨C5 irradiation 383¨C4 lipoic acid 236 Listeria monocytogenes 351¨C2, 373 lycopene 197 Index 479 lysine 273¨C4 lysinoalanine (LAL) 277, 279¨C80 magnesium sodium 98 Maillard reaction 266¨C75, 280¨C2 and extrusion cooking 320 manganese 129 margarines 198¨C200 marketing functional foods 310¨C11 and nutrition claims 147 meat availability 22, 25¨C6 and bone health 235 and cancer 210, 211¨C14 colour retention 345 consumption trends 210¨C11 fat components 214¨C23, 234 freezing 336¨C7 health-promoting components 235¨C6 high pressure processing 444¨C5 iron content 228¨C30, 235 nutritional importance 209¨C10 Palaeolithic diets 226¨C7 phosphorus content 231 protein content 223¨C4 satiating powers 227 selenium content 230¨C1, 235 vitamin B content 231¨C2 vitamin D content 232¨C3 zinc content 230 mechanical processing 302¨C5 Mediterranean diets 25, 28¨C9, 196, 213 melanoidins 275¨C7, 281 menadione 57 Menkes disease 121¨C2, 131 methylation cycle 71, 72 methylmalonic acid (MMA) 79¨C80 microbial safety 350¨C4, 373, 411 microwave processing 396¨C406 effect on food 401¨C3 industrial exploitation 405¨C6 nutritional adequacy of food 405 principles 398¨C401 safety 403¨C5 milk 250, 253, 255¨C7, 261, 468¨C9, 470 milling 302¨C5 abrasive processes 303¨C4 reductive processes 304 minerals 97¨C113 absorption 98¨C9, 103, 105, 108 bioavailability 323¨C4 calcium 98, 102¨C5 copper see copper dietary sources 100¨C2 extrusion cooking 323¨C4 fluoride 98 food fortification 102, 324 frying 297 high pressure processing 445¨C6 iodine 98, 99, 102, 111 iron 98, 99, 105¨C7 magnesium sodium 98 molybdenum 98, 129 nutrition labelling 145¨C6 phosphorus 98 potassium 98 reference nutrient intake 97¨C8, 100 safe intakes 100 selenium 99, 111¨C13 supplements 101 zinc 99, 107¨C10, 129 modified atmosphere packaging (MAP) 342¨C62 anaerobic respiration 346 use of carbon dioxide 343¨C5, 346¨C7 colour retention of meat products 345 equilibrium modified atmosphere packaging 347¨C50 fruits 356¨C62 microbial safety 350¨C4 non-respiring products 346¨C7, 354¨C5 optimal gas atmosphere 346¨C7 use of oxygen 345¨C6 and provitamin carotenoids 358¨C9 respiring products 347¨C50 trimethylamineoxide reduction 345¨C6 vegetables 356¨C62 vitamin C 356¨C8 molybdenum 98, 129 MONICA Project 20 monoacylglycerols 294 monoamine oxidase 119 monounsaturated fatty acids 218 mutagenic heterocyclic amines (HAs) 282¨C5 near infrared heating (NIR) 424 neural tube defects 70, 72¨C4, 203 niacin 82¨C3, 231, 255 food sources 37 and irradiation 380, 381¨C2 reference nutrient intake 36 nicotinamide 82¨C3 nicotinic acid 82¨C3 night blindness 35 480 Index non-respiring products 346¨C7, 354¨C5 nuclear receptors 40 nucleotides 236 nutrition claims 147 nutrition information panels 151¨C6 Nutrition Labelling Directive 144¨C9 declared values 146¨C7 definitions 146 energy value calculations 146 format of information 145¨C6 implementation and enforcement 148 and nutrition claims 147 timescales 147 nutritional enhancement 196¨C206 and bioavailability 201¨C2 of cereal foods 308¨C11 compared to fortification 202¨C3 genetic engineering 197¨C8, 200¨C1, 204¨C6 pedigree selection and backcross programmes 197 reducing antinutritional factors 197 supplements 198 nutritional melalgia 81¨C2 obesity 234 ohmic heating 407¨C19 advantages 409¨C12 cold spots 411¨C12, 419 commercialisation 416¨C17 electrical conductivity and heating rate 410¨C11 and electrolysis 416 enhanced diffusion 415¨C16 microbial destruction 411 modelling heating patterns 417¨C18 nutrient loss 413¨C16, 417 principles 407¨C9 process parameters 418 product specifications 418 temperature distribution 411¨C12, 419 1,25-OHD 48¨C50, 103 osteocalcin 50¨C1, 58 osteomalacia 233 osteoporosis 50¨C1, 60, 103¨C4 Ostwald ripening 333 oxygen 345¨C6 Palaeolithic diets 226¨C7 pantothenic acid 37, 81¨C2, 255 pedigree selection 197 pellagra 83 peptidyl-glycine ¦Ì-amidating mono- oxygenase (PAM) 119 phenolic compounds 325, 359¨C61 phosphorus 98, 231 phytates 197 phytohormones 325 plasma homocysteine 72, 75¨C6, 80, 84¨C5 polyunsaturated fatty acids 219¨C21 pork lard 295 postprandial glycaemia 173¨C4 potassium 98 pressure treated foods see high pressure processing product shelf life 262¨C3 proteins 154¨C5, 297 continuous-flow heat processing 468¨C9 extrusion cooking 320¨C1 irradiation 384 meat content 223¨C4 provitamin carotenoids see carotenoids pyridoxine 83¨C5, 256¨C7 and irradiation 380, 381¨C2 pyrolysis products 282¨C3 radiation processing see irradiation radioisotopes 133, 134 receptors 60 recommended dietary allowance (RDA) 34¨C5 reference nutrient intake (RNI) calcium 104 copper 120 folates 36, 72, 74 iodine 111 iron 106¨C7 minerals 97¨C8, 100 niacin 36 riboflavin 36 selenium 112 thiamin 36 vitamin A 35, 36, 38 vitamin B 36 vitamin C 36 vitamin D 36 zinc 109 regulation of flour production 304¨C5 of irradiation 386¨C90 Nutrition Labelling Directive 144¨C9 relative glycaemic potency (RGP) 174¨C80 resistant starch 307¨C8 respiring products 347¨C50 Index 481 retinol 35, 40¨C1, 44, 45, 381 and high pressure processing 441 see also vitamin A retrograded starch 308 riboflavin 85¨C6, 231, 254¨C5, 255, 413 food sources 37, 85 and irradiation 380, 381¨C2 reference nutrient intake 36 rice 200¨C1 rickets 47, 233 safe intakes (SI) calcium 105 cobalamins 80 copper 117, 122¨C4 folates 76¨C7 iodine 111 iron 107 minerals 100 selenium 113 thiamin 70 vitamin A 44¨C6 vitamin C 66 vitamin D 52 vitamin E 56 vitamin K 61 zinc 110 safety of high pressure processing 434¨C5 of irradiation 378¨C9, 385 microbial safety 350¨C4, 373, 411 of microwave processing 403¨C5 of thermal processing 282¨C5 Salmonella 373 salt 155 satiety 227 saturated fatty acids 218 scurvy 62 seasonal affective disorders (SAD) 51 selenium 99, 111¨C13, 230¨C1, 235 reference nutrient intake 112 safe intake 113 selenosis 99, 113 SENECA see Euronut-SENECA study serum copper 125¨C6 shallow frying 293 shelf life of products 262¨C3 short-wave infrared heating 424 smokers 63¨C4 sodium intake 155 starches 306¨C8, 318, 414, 469 steam infusion 465 steam injection 465 sterilisation 463¨C4 Strecker degradation 269 sugars 175, 273, 317 superoxide dismutase (SOD) 119 supplements 101, 195, 198 surveys see data sources sweeteners 445 thermal degradation kinetics 463¨C4 thermal processing 265¨C85, 407, 462 of cereal foods 303, 305¨C8 cross-linked amino acids formation 277¨C80 Maillard reaction 266¨C75, 280¨C2 melanoidins 275¨C7, 281 molecular level reactions 265¨C6 thermal degradation kinetics 463¨C4 toxic compound formation 282¨C5 and vitamin loss 261 see also continuous-flow heat processing; ohmic heating thiamin 66¨C70, 231, 253¨C4, 413 deficiency effects 68¨C70 extrusion cooking 323 food sources 37, 67 functions and requirements 67¨C8 irradiation 380, 381¨C2 reference nutrient intake 36 toxicity 70 thioredoxin 197 tocopherols 52¨C3, 297, 383 see also vitamin E tocotrienols 52 toxicity see safe intakes (SI) trans-fatty acids 222 TRANSFAIR study 21¨C2 triacylglycerols 294 trimethylamineoxide reduction 345¨C6 Tyrolean Infantile Cirrhosis (ICC) 124 tyrosinase 119 UHT milk 250, 253, 256¨C7, 261, 468¨C9 validation of tests 172 vascular cell dysfunction 56 vegetable oils 24, 26, 443 vegetables availability 22, 25 and cancer protection 44, 65 and cardiovascular disease 65, 75¨C6 cooking methods 335¨C6 and copper absorption 128 freezing 333¨C6 high pressure processing 446 482 Index modified atmosphere packaging 356¨C62 storage after harvest 334 washing and blanching 334¨C5, 338 vegetarians 51, 195, 224¨C6 vision 35, 40 night blindness 35 vitamin A 35¨C46, 248 bioavailability 38 bioefficacy 38¨C9 continuous-flow heat processing 470¨C1 deficiency disorders (VADD) 35, 38, 44, 196, 200 equivalence factor 39¨C40 food sources 37 health aspects 35, 38, 40¨C4 high pressure processing 440¨C1 hypervitaminosis A 44¨C5 and the immune system 41¨C2, 43 irradiation 380, 381 ohmic heating 413 reference nutrient intake 35, 36, 38 stability during processing 249¨C51 toxicity symptoms 44¨C5 vitamin B cobalamins (B 12 ) 77¨C80, 257 continuous-flow heat processing 470¨C1 food sources 37 frying 297 high pressure processing 441¨C2 irradiation 380, 381¨C2 in meat 231¨C2 ohmic heating 413 pyridoxine (B 6 ) 83¨C5, 256¨C7 reference nutrient intake 36 riboflavin (B 2 ) 85¨C6, 254¨C5 stability during processing 253¨C7 thiamin (B 1 ) 66¨C70, 253¨C4 vitamin C 62¨C6 absorption 62 biochemical functions 63 continuous-flow heat processing 470¨C1 disease-nutrient interactions 63¨C5 food sources 37 health aspects 62, 63¨C6 high pressure processing 437, 440 and the immune system 65¨C6 iron/vitamin C reaction 64 irradiation 380, 382 modified atmosphere packaging (MAP) 356¨C8 ohmic heating 413 reference nutrient intake 36 and smokers 63¨C4 stability during processing 258¨C9 toxicity 66 vitamin D 46¨C52 and bone health 50¨C1 continuous-flow heat processing 470 food sources 37 health aspects 47¨C52 and the immune system 51¨C2 irradiation 382¨C3 in meat 232¨C3 ohmic heating 413 1,25-OHD 48¨C50 reference nutrient intake 36 safety 52 stability during processing 251¨C2 vitamin E 52¨C7, 247¨C8 bioactivity 53 continuous-flow heat processing 470 food sources 37, 52 health aspects 53¨C6 and heart disease 53¨C5 high pressure processing 441¨C2 and the immune system 55¨C6 irradiation 383 safety 56 stability during processing 251 vitamin K 57¨C61 biological activity 57¨C9 and bone health 58¨C9, 60¨C1 food sources 37, 57 health aspects 59¨C61 high pressure processing 441¨C2 ohmic heating 413 safety 61 stability during processing 252¨C3 vitamins blanching 260¨C1 continuous-flow heat processing 470¨C1 and dehydration 262 extrusion cooking 321¨C3 freezing 261 frying 297 high pressure processing 437¨C42 irradiation 262, 380¨C3 labelling 145¨C6, 249 loss during processing 260¨C2 ohmic heating 407, 413 and product shelf life 262¨C3 protecting 263 stability during processing 247¨C59 Index 483 as supplements 195 thermal processing 261, 305¨C6 vitamin-vitamin interactions 259¨C90 Wernicke-Korsakoff syndrome 69 wet extrusion 316¨C17 wheat bran equivalents 180¨C6 WHO-MONICA Project 20 wholesomeness of irradiated food 384¨C5 Wilson¡¯s disease 124 World Trade Organization (WTO) 389¨C90 X-Rays 374¨C5, 377, 378 xenobiotic enzymes 281¨C2 Yersinia enterocolitica 352¨C3 zinc 99, 107¨C10, 129 absorption 108 deficiency 109 meat content 230 reference nutrient intake 109 safe intake 110