absorption of Amadori compounds 280 of calcium 103 of copper 117, 127每33 of iron 105 of Maillard reaction products 280每1 of melanoidins 281 of minerals 98每9, 103, 105, 108 of vitamin C 62 of zinc 108 advertising functional foods 310每11 nutrition claims 147 Aeromonas species of bacteria 354, 355 alcohol consumption 9, 69 allergens 447每8 Alzheimer*s disease 82 Amadori rearrangement products (ARPs) 266每9, 280 amine oxidases 119 amino acids 271, 273 cross-linked 277每80 amino-carbalines 282每3 amino-imidazo-azaarenes (AIAs) 283 anaemia 78, 99, 106, 228 anaerobic respiration 346 analytical systems see functionality testing anti-freeze peptides 339 anti-mutagenic compounds 446 antinutrients 197, 324每5 antioxidants 42, 52每4, 63每4, 281, 294 ascorbic acid 62, 258每9, 297, 322每3 and high pressure processing 437, 440 and irradiation 382 see also vitamin C Asian communities 47, 51 atherosclerosis 178 b-carbolines 283 b-carotene 35, 39每40, 42每6, 64每5, 250每1, 358每9 backcross programmes 197 bacteria 350每4, 373, 411 bakery products 427每30 beriberi 66每9 bioactivity 53, 57每9, 168每9 bioavailability of nutrients 169, 201每2 in cereal foods 302每3 copper 128每9 folates 71 iron 130, 228 minerals 323每4 vitamin A 38 bioefficacy of vitamin A 38每9 biogenic amines 236 biomarkers 171每2, 174每5, 181 biotin 37, 80每1, 257 and irradiation 380, 381每2 blanching 334每5, 338, 415每16 and vitamin loss 260每1 Index Index 475 blood clotting 57每8, 59 blood glucose 170, 174每5 bone health and meat 235 osteoporosis 50每1, 60, 103每4 and vitamin D 50每1 and vitamin K 58每9, 60每1 caeruloplasmin 119 calciferol 46, 48每50 and irradiation 382每3 see also vitamin D calcium 50, 58每9, 98, 102每5 absorption 103 food sources 104 reference nutrient intake 104 safe intake 105 CALEUR study 21 calorific information 155 Campylobacter 373 cancer 9, 18每19, 44, 209 and antioxidants 52 and b-carotene 42每4 colon cancer 51, 211每14 and meat eating 210, 211每14 carbohydrates 154, 173每4, 175, 306每8 and continuous-flow heat processing 469每70 and extrusion cooking 317每19 and irradiation 383 carbon dioxide 343每5, 346每7 cardiovascular disease (CVD) see heart disease carnitine 236 carnosine 236 carotenoids b-carotene 35, 39每40, 42每6, 64每5, 250每1, 358每9 and high pressure processing 440每1 and irradiation 380 and modified atmosphere packaging 358每9 catechol oxidase 119 cell differentiation 40 cellular growth 51 cereal foods 22, 102, 166, 185每6, 301每11 bioavailability of nutrients 302每3 mechanical processing 302每5 nutritional significance 302每3 nutritionally enhanced 308每11 thermal processing 303, 305每8 cholesterol 198每200, 214每15, 223, 296, 320 LDL-cholesterol oxidation 54 choline 236 Clostridium botulinum 351 cobalamins 77每80, 257 deficiency diseases 78每9 food sources 37, 77 and irradiation 380, 381每2 toxicity 80 Codex Alimentarius 388, 389每90 coeliac disease 48 cold spots 411每12, 419 colon cancer 51, 211每14 colonic bulk 181 colour of foods 276每7, 345 conjugated linoleic acid (CLA) 221每3 consumers food choice factors 149, 150每1, 168 improving consumer confidence 168 understanding of labelling 149每56 continuous-flow heat processing 462每72 and carbohydrates 469每70 commercialisation 471每2 and fats 469每70 flash-cooling 466 food quality 466每8 heat exchanger selection 464每6 and proteins 468每9 steam infusion 465 steam injection 465 streamline flow 468 technical problems 472 thermal degradation kinetics 463每4 time-temperature profile 466每7 turbulent flow 468 and vitamins 470每1 copper 65, 117每35 absorption 117, 127每33 bioavailability 128每9 deficiency diseases 117, 121每2 distribution in the body 131 in drinking water 123 food sources 120每1 function of cuproenzymes 118每20 functional copper status 127 and heart disease 122 intake assessment 124每7 putative indicators 125每6 reference nutrient intake 120 serum copper 125每6 toxicity 117, 122每4 coronary heart disease (CHD) see heart disease cross-linked amino acids 277每80 476 Index cuproenzymes 118每20 cyanocobalamin 380, 381每2 cytochrome-c oxidase 118 DAFNE (DAta Food NEtworking) project 11, 17每18 dairy products 128, 446, 447 data sources 7, 10每22 European surveys 13每22 food balance sheets (FBS) 10, 22 food frequency questionnaires 13 household budget surveys (HBS) 11每12, 17每18 individual dietary surveys (IDSs) 12每13 deep frying 293, 298 dehydration, and vitamin loss 262 dephytinisation 130 diabetes 48, 172, 174每5, 178 diacylglycerols 294 diamine oxidase 119 diet data sources 7, 10每22 European dietary patterns 22每8 Mediterranean countries 25, 28每9, 196, 213 and health 8每10 nutrition and the elderly 20每1 dietary reference values 34每5 digestibility of food 446每7 disease-nutrient interactions 63每5 DNA damage and repair 56 dopamine b-hydroxylase (DbM) 119 drinking water 123 drip loss 333, 336 elderly people 20每1, 47每8 and antioxidant vitamins 64 immune system 55每6 electrolysis 416 electromagnetic radiation 397 electrons 374每5, 377 embryogenesis 41 end-points 171, 174, 181 energy information provision 155 value calculations 146 enhanced diffusion 415每16 enhancement see nutritional enhancement enzymes 320 cuproenzymes 118每20 xenobiotic enzymes 281每2 see also Maillard reaction equilibrium modified atmosphere packaging (EMAP) 347每50 Escherichia coli 373, 386, 390 Euronut-SENECA study 20每1, 28 European dietary patterns 22每8 Mediterranean countries 25, 28每9, 196, 213 European Prospective Investigation into Cancer and Nutrition (EPIC) 18每19, 28 European surveys 13每22 extrusion cooking 314每26 and antinutrients 324每5 and carbohydrates 317每19 future trends 325每6 and lipids 321 Maillard reactions 320 and minerals 323每4 and phenolic compounds 325 and phytohormones 325 and proteins 320每1 and thiamin 323 vitamin stability 321每3 wet extrusion 316每17 faecal bulk 171, 180每6 fats and continuous-flow heat processing 469每70 and frying 293 information provision 153, 154 in meat 214每23, 234 fatty acids 217每22 and cholesterol 223 conjugated linoleic acid (CLA) 221每3 monounsaturated fatty acids 218 polyunsaturated fatty acids 219每21 saturated fatty acids 218 trans-fatty acids 222 ferroxidases 119 fibre 155, 166, 181每2, 309, 319 fish freezing 336每7 high pressure processing 443每4 trimethylamineoxide reduction 345每6 flash-cooling 466 flavonoids 202 flour production 304每5 fluoride 98 folates 70每7, 202每3, 256 bioavailability 71 Index 477 and cardiovascular disease (CVD) 75每6 deficiency effects 76 food sources 37, 70每1 fortification of foods 74每5, 77 reference nutrient intake 36, 72, 74 requirements 72每5 toxicity 76每7 food balance sheets (FBS) 10, 22 food frequency questionnaires 13 food matrix properties 170 Food Standards Agency (FSA) 160每1 fortification 195, 202每3 with folates 74每5, 77 with minerals 102, 324 see also nutritional enhancement fractures see bone health freezing 331每40 anti-freeze peptides 339 drip loss 333, 336 fruit 333每6 &glassy state* freezing 338每9 meat and fish 336每7 Ostwald ripening 333 quality and nutrient loss 332每3 vegetables and fruit 333每6 and vitamin loss 261 fruit availability 24, 25 and cancer protection 44, 65 and cardiovascular disease 65, 75每6 cooking methods 335每6 high pressure processing 446 modified atmosphere packaging 356每62 storage after harvest 334 washing and blanching 334每5, 338 frying 293每8 deep frying 293, 298 and fat consumption 293 frying oil 294每5, 298 impact on nutrients 296每7 meat 428每30 sensory characteristics 297每8 shallow frying 293 FSA (Food Standards Agency) 160每1 functional foods market for 186每7 marketing 310每11 functionality testing biomarkers 171每2, 174每5, 181 data limitations 168每9, 173每4 end-points 171, 174, 181 extrapolation between products 167 food matrix properties 170 food processing and nutritional quality 165每7 future trends 186每8 glycaemic-glucose equivalents 174每80 indices 172每3 faecal bulking index 180每6 glycaemic index (GI) 173, 175每9 market for functional foods 186每7 types of tests 167 validation of tests 172 wheat bran equivalents 180每6 gamma rays 374, 375 genetic engineering 197每8, 200每1, 204每6 &glassy state* freezing 338每9 glucosinolates 325, 361每2 glutathione 236 glycaemic index (GI) 173, 175每9, 307 glycaemic-glucose equivalents 174每80 goitre 99, 111, 196 Grasbeck-Immerslund syndrome 78 Guideline Daily Amounts (GDAs) 158每9 haemorrhagic disease of the newborn (HDN) 59每60 hair colour 82 haptocorrins 78 heart disease cardiovascular disease 8每9, 20, 75每6, 122 and copper deficiency 122 coronary heart disease 9, 20, 53每5 vascular cell dysfunction 56 and vitamin E 53每5 heat exchangers 464每6 heat processing see thermal processing hephaestin 131 heterocyclic amines (HAs) 282每5 high pressure processing 433每61 and allergens 447每8 anti-mutagenic compounds 446 and ascorbic acid 437, 440 and carotene 440每1 commercial food products 436, 438每9 dairy products 446, 447 digestibility of food 446每7 equipment 435每6 fish products 443每4 food quality 433每4 478 Index fruit 446 future trends 448 and lipids 442每5 meat products 444每5 and mineral content 445每6 and retinol 441 safety 434每5 and sweeteners 445 vegetables 446 and vitamins 437每42 histidinoalanine (HAL) 278每9, 279每80 homocysteine 72, 75每6, 80, 84每5 household budget surveys (HBS) 11每12, 17每18 Hox family genes 41 hunter-gatherer diets 227 hydroperoxides 294每5, 384 hyperglycaemia 174 hypervitaminosis A 44每5 immune system and elderly people 55每6 and vitamin A 41每2, 43 and vitamin C 65每6 and vitamin D 51每2 and vitamin E 55每6 and zinc deficiency 109 Indian Childhood Cirrhosis (ICC) 124 indices 172每3 faecal bulking index 180每6 glycaemic index (GI) 173, 175每9 individual dietary surveys (IDSs) 12每13 infants, haemorrhagic disease of the newborn (HDN) 59每60 information panels 151每6 infrared heating 398, 423每31 bakery products 427每30 food industry applications 426每7 food quality 428每30 frying meat 428每30 future trends 430每1 near infrared heating (NIR) 424 nutritional quality 430 penetration depths 426 iodine 98, 99, 102, 111 deficiency disorders 8, 196 ionising radiation see irradiation iron 64每5, 98, 99, 105每7 absorption 105 bioavailability 130, 228 deficiency diseases 228 food sources 107 iron/vitamin C reaction 64 in meat 228每30, 235 reference nutrient intake 106每7 safe intake 107 irradiation 371每92 and ascorbic acid 382 benefits 385每6 and biotin 380, 381每2 and calciferol 382每3 and carbohydrates 383 and carotenoids 380 and cobalamins 381每2 consumer attitudes to 386每9 and cyanocobalamin 380, 381每2 effect on food 377每8 future trends 390每1 history of 372每3 and lipids 383每4 and niacin 380, 381每2 nutritional adequacy 379每80 principles of 373每7 and proteins 384 and pyridoxine 380, 381每2 regulation of 386每90 and riboflavin 380, 381每2 safety of 378每9, 385 and thiamin 380, 381每2 and tocopherols 383 and vitamins 262, 380每3 wholesomeness of irradiated food 384每5 isotope studies 132每3 Keshan disease 112 Korsakoff syndrome 69 labelling 142每63 consumer understanding of 149每56 future trends in 161每3 Guideline Daily Amounts (GDAs) 158每9 legibility 160 nutrition information panels 151每6 Nutrition Labelling Directive 144每9 research findings 157每61 retailer influence on 149每50 LDL-cholesterol oxidation 54 legislation see regulation lipids 24每5, 297 extrusion cooking 321 high pressure processing 442每5 irradiation 383每4 lipoic acid 236 Listeria monocytogenes 351每2, 373 lycopene 197 Index 479 lysine 273每4 lysinoalanine (LAL) 277, 279每80 magnesium sodium 98 Maillard reaction 266每75, 280每2 and extrusion cooking 320 manganese 129 margarines 198每200 marketing functional foods 310每11 and nutrition claims 147 meat availability 22, 25每6 and bone health 235 and cancer 210, 211每14 colour retention 345 consumption trends 210每11 fat components 214每23, 234 freezing 336每7 health-promoting components 235每6 high pressure processing 444每5 iron content 228每30, 235 nutritional importance 209每10 Palaeolithic diets 226每7 phosphorus content 231 protein content 223每4 satiating powers 227 selenium content 230每1, 235 vitamin B content 231每2 vitamin D content 232每3 zinc content 230 mechanical processing 302每5 Mediterranean diets 25, 28每9, 196, 213 melanoidins 275每7, 281 menadione 57 Menkes disease 121每2, 131 methylation cycle 71, 72 methylmalonic acid (MMA) 79每80 microbial safety 350每4, 373, 411 microwave processing 396每406 effect on food 401每3 industrial exploitation 405每6 nutritional adequacy of food 405 principles 398每401 safety 403每5 milk 250, 253, 255每7, 261, 468每9, 470 milling 302每5 abrasive processes 303每4 reductive processes 304 minerals 97每113 absorption 98每9, 103, 105, 108 bioavailability 323每4 calcium 98, 102每5 copper see copper dietary sources 100每2 extrusion cooking 323每4 fluoride 98 food fortification 102, 324 frying 297 high pressure processing 445每6 iodine 98, 99, 102, 111 iron 98, 99, 105每7 magnesium sodium 98 molybdenum 98, 129 nutrition labelling 145每6 phosphorus 98 potassium 98 reference nutrient intake 97每8, 100 safe intakes 100 selenium 99, 111每13 supplements 101 zinc 99, 107每10, 129 modified atmosphere packaging (MAP) 342每62 anaerobic respiration 346 use of carbon dioxide 343每5, 346每7 colour retention of meat products 345 equilibrium modified atmosphere packaging 347每50 fruits 356每62 microbial safety 350每4 non-respiring products 346每7, 354每5 optimal gas atmosphere 346每7 use of oxygen 345每6 and provitamin carotenoids 358每9 respiring products 347每50 trimethylamineoxide reduction 345每6 vegetables 356每62 vitamin C 356每8 molybdenum 98, 129 MONICA Project 20 monoacylglycerols 294 monoamine oxidase 119 monounsaturated fatty acids 218 mutagenic heterocyclic amines (HAs) 282每5 near infrared heating (NIR) 424 neural tube defects 70, 72每4, 203 niacin 82每3, 231, 255 food sources 37 and irradiation 380, 381每2 reference nutrient intake 36 nicotinamide 82每3 nicotinic acid 82每3 night blindness 35 480 Index non-respiring products 346每7, 354每5 nuclear receptors 40 nucleotides 236 nutrition claims 147 nutrition information panels 151每6 Nutrition Labelling Directive 144每9 declared values 146每7 definitions 146 energy value calculations 146 format of information 145每6 implementation and enforcement 148 and nutrition claims 147 timescales 147 nutritional enhancement 196每206 and bioavailability 201每2 of cereal foods 308每11 compared to fortification 202每3 genetic engineering 197每8, 200每1, 204每6 pedigree selection and backcross programmes 197 reducing antinutritional factors 197 supplements 198 nutritional melalgia 81每2 obesity 234 ohmic heating 407每19 advantages 409每12 cold spots 411每12, 419 commercialisation 416每17 electrical conductivity and heating rate 410每11 and electrolysis 416 enhanced diffusion 415每16 microbial destruction 411 modelling heating patterns 417每18 nutrient loss 413每16, 417 principles 407每9 process parameters 418 product specifications 418 temperature distribution 411每12, 419 1,25-OHD 48每50, 103 osteocalcin 50每1, 58 osteomalacia 233 osteoporosis 50每1, 60, 103每4 Ostwald ripening 333 oxygen 345每6 Palaeolithic diets 226每7 pantothenic acid 37, 81每2, 255 pedigree selection 197 pellagra 83 peptidyl-glycine 米-amidating mono- oxygenase (PAM) 119 phenolic compounds 325, 359每61 phosphorus 98, 231 phytates 197 phytohormones 325 plasma homocysteine 72, 75每6, 80, 84每5 polyunsaturated fatty acids 219每21 pork lard 295 postprandial glycaemia 173每4 potassium 98 pressure treated foods see high pressure processing product shelf life 262每3 proteins 154每5, 297 continuous-flow heat processing 468每9 extrusion cooking 320每1 irradiation 384 meat content 223每4 provitamin carotenoids see carotenoids pyridoxine 83每5, 256每7 and irradiation 380, 381每2 pyrolysis products 282每3 radiation processing see irradiation radioisotopes 133, 134 receptors 60 recommended dietary allowance (RDA) 34每5 reference nutrient intake (RNI) calcium 104 copper 120 folates 36, 72, 74 iodine 111 iron 106每7 minerals 97每8, 100 niacin 36 riboflavin 36 selenium 112 thiamin 36 vitamin A 35, 36, 38 vitamin B 36 vitamin C 36 vitamin D 36 zinc 109 regulation of flour production 304每5 of irradiation 386每90 Nutrition Labelling Directive 144每9 relative glycaemic potency (RGP) 174每80 resistant starch 307每8 respiring products 347每50 Index 481 retinol 35, 40每1, 44, 45, 381 and high pressure processing 441 see also vitamin A retrograded starch 308 riboflavin 85每6, 231, 254每5, 255, 413 food sources 37, 85 and irradiation 380, 381每2 reference nutrient intake 36 rice 200每1 rickets 47, 233 safe intakes (SI) calcium 105 cobalamins 80 copper 117, 122每4 folates 76每7 iodine 111 iron 107 minerals 100 selenium 113 thiamin 70 vitamin A 44每6 vitamin C 66 vitamin D 52 vitamin E 56 vitamin K 61 zinc 110 safety of high pressure processing 434每5 of irradiation 378每9, 385 microbial safety 350每4, 373, 411 of microwave processing 403每5 of thermal processing 282每5 Salmonella 373 salt 155 satiety 227 saturated fatty acids 218 scurvy 62 seasonal affective disorders (SAD) 51 selenium 99, 111每13, 230每1, 235 reference nutrient intake 112 safe intake 113 selenosis 99, 113 SENECA see Euronut-SENECA study serum copper 125每6 shallow frying 293 shelf life of products 262每3 short-wave infrared heating 424 smokers 63每4 sodium intake 155 starches 306每8, 318, 414, 469 steam infusion 465 steam injection 465 sterilisation 463每4 Strecker degradation 269 sugars 175, 273, 317 superoxide dismutase (SOD) 119 supplements 101, 195, 198 surveys see data sources sweeteners 445 thermal degradation kinetics 463每4 thermal processing 265每85, 407, 462 of cereal foods 303, 305每8 cross-linked amino acids formation 277每80 Maillard reaction 266每75, 280每2 melanoidins 275每7, 281 molecular level reactions 265每6 thermal degradation kinetics 463每4 toxic compound formation 282每5 and vitamin loss 261 see also continuous-flow heat processing; ohmic heating thiamin 66每70, 231, 253每4, 413 deficiency effects 68每70 extrusion cooking 323 food sources 37, 67 functions and requirements 67每8 irradiation 380, 381每2 reference nutrient intake 36 toxicity 70 thioredoxin 197 tocopherols 52每3, 297, 383 see also vitamin E tocotrienols 52 toxicity see safe intakes (SI) trans-fatty acids 222 TRANSFAIR study 21每2 triacylglycerols 294 trimethylamineoxide reduction 345每6 Tyrolean Infantile Cirrhosis (ICC) 124 tyrosinase 119 UHT milk 250, 253, 256每7, 261, 468每9 validation of tests 172 vascular cell dysfunction 56 vegetable oils 24, 26, 443 vegetables availability 22, 25 and cancer protection 44, 65 and cardiovascular disease 65, 75每6 cooking methods 335每6 and copper absorption 128 freezing 333每6 high pressure processing 446 482 Index modified atmosphere packaging 356每62 storage after harvest 334 washing and blanching 334每5, 338 vegetarians 51, 195, 224每6 vision 35, 40 night blindness 35 vitamin A 35每46, 248 bioavailability 38 bioefficacy 38每9 continuous-flow heat processing 470每1 deficiency disorders (VADD) 35, 38, 44, 196, 200 equivalence factor 39每40 food sources 37 health aspects 35, 38, 40每4 high pressure processing 440每1 hypervitaminosis A 44每5 and the immune system 41每2, 43 irradiation 380, 381 ohmic heating 413 reference nutrient intake 35, 36, 38 stability during processing 249每51 toxicity symptoms 44每5 vitamin B cobalamins (B 12 ) 77每80, 257 continuous-flow heat processing 470每1 food sources 37 frying 297 high pressure processing 441每2 irradiation 380, 381每2 in meat 231每2 ohmic heating 413 pyridoxine (B 6 ) 83每5, 256每7 reference nutrient intake 36 riboflavin (B 2 ) 85每6, 254每5 stability during processing 253每7 thiamin (B 1 ) 66每70, 253每4 vitamin C 62每6 absorption 62 biochemical functions 63 continuous-flow heat processing 470每1 disease-nutrient interactions 63每5 food sources 37 health aspects 62, 63每6 high pressure processing 437, 440 and the immune system 65每6 iron/vitamin C reaction 64 irradiation 380, 382 modified atmosphere packaging (MAP) 356每8 ohmic heating 413 reference nutrient intake 36 and smokers 63每4 stability during processing 258每9 toxicity 66 vitamin D 46每52 and bone health 50每1 continuous-flow heat processing 470 food sources 37 health aspects 47每52 and the immune system 51每2 irradiation 382每3 in meat 232每3 ohmic heating 413 1,25-OHD 48每50 reference nutrient intake 36 safety 52 stability during processing 251每2 vitamin E 52每7, 247每8 bioactivity 53 continuous-flow heat processing 470 food sources 37, 52 health aspects 53每6 and heart disease 53每5 high pressure processing 441每2 and the immune system 55每6 irradiation 383 safety 56 stability during processing 251 vitamin K 57每61 biological activity 57每9 and bone health 58每9, 60每1 food sources 37, 57 health aspects 59每61 high pressure processing 441每2 ohmic heating 413 safety 61 stability during processing 252每3 vitamins blanching 260每1 continuous-flow heat processing 470每1 and dehydration 262 extrusion cooking 321每3 freezing 261 frying 297 high pressure processing 437每42 irradiation 262, 380每3 labelling 145每6, 249 loss during processing 260每2 ohmic heating 407, 413 and product shelf life 262每3 protecting 263 stability during processing 247每59 Index 483 as supplements 195 thermal processing 261, 305每6 vitamin-vitamin interactions 259每90 Wernicke-Korsakoff syndrome 69 wet extrusion 316每17 wheat bran equivalents 180每6 WHO-MONICA Project 20 wholesomeness of irradiated food 384每5 Wilson*s disease 124 World Trade Organization (WTO) 389每90 X-Rays 374每5, 377, 378 xenobiotic enzymes 281每2 Yersinia enterocolitica 352每3 zinc 99, 107每10, 129 absorption 108 deficiency 109 meat content 230 reference nutrient intake 109 safe intake 110